Evidence map›Paper›PMID 32346511›Full record

ArticleMetabolic engineering communications2020

Metabolic engineering of an acid-tolerant yeast strain

Wan Sun, Ana Vila-Santa, Na Liu, Tanya Prozorov, Dongming Xie, Nuno Torres Faria, Frederico Castelo Ferreira, Nuno Pereira Mira, Zengyi Shao

Open access · goldAbstract read
In one paragraph

Article in Metabolic engineering communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 82 citations in OpenAlex.

  1. Production, Optimization and Characterization of Biobased Itaconic Acid fromInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. A versatile genetic toolkit for engineeringFrontiers in bioengineering and biotechnology · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Genome sequencing of 15 acid-tolerant yeasts.Microbiology resource announcements · 2023
    Article
  14. Article
  15. Metabolic engineering of low-pH-tolerant non-model yeast,Metabolic engineering communications · 2023
    Article
  16. Schwanniomyces etchellsii, acid-thermotolerant yeasts from urban city soil.World journal of microbiology & biotechnology · 2023
    Article
  17. Advances in the Application of the Non-Conventional YeastJournal of fungi (Basel, Switzerland) · 2023
    Review
  18. Itaconic acid production is regulated by LaeA inMetabolic engineering communications · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Wan SunInterdepartmental Microbiology Program, Iowa State University, Ames, USA.
Ana Vila-SantaDepartment of Bioengineering, Instituto Superior Técnico, Lisbon, Portugal.
Na LiuDepartment of Chemical Engineering, University of Massachusetts, Lowell, MA, USA.
Tanya ProzorovAmes Laboratory, U.S. Department of Energy, Ames, Iowa, USA.
Dongming XieDepartment of Chemical Engineering, University of Massachusetts, Lowell, MA, USA.
Nuno Torres FariaDepartment of Bioengineering, Instituto Superior Técnico, Lisbon, Portugal.
Frederico Castelo FerreiraDepartment of Bioengineering, Instituto Superior Técnico, Lisbon, Portugal.
Nuno Pereira MiraDepartment of Bioengineering, Instituto Superior Técnico, Lisbon, Portugal.
Zengyi ShaoInterdepartmental Microbiology Program, Iowa State University, Ames, USA.
Ames National Laboratory · USInstitute for Biotechnology and Bioengineering · PTInstituto Superior TécnicoUniversity of Massachusetts Lowell · USIowa State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Itaconic acid (IA), or 2-methylenesuccinic acid, has a broad spectrum of applications in the biopolymer industry owing to the presence of one vinyl bond and two acid groups in the structure. Its polymerization can follow a similar mechanism as acrylic acid but additional functionality can be incorporated into the extra beta acid group. Currently, the bio-based production of IA in industry relies on the fermentation of the filamentous fungus

Indexed as

Acid toleranceBiopolymersIssatchenkia orientalisItaconic acidNon-conventional microorganismsPichia kudriavzevii

Identifiers

PMID32346511
PMCPMC7178482
OpenAlexW3006043636

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.