ArticleNano today2020
Active matter therapeutics.
Article in Nano today, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Tracking inflammation status for improving patient prognosis: A review of current methods, unmet clinical needs and opportunities.Biotechnology advances · 2025Review
- Applications of nanomaterials in head and neck squamous cell carcinoma: current progress and perspectives.Discover nano · 2025Review
- Active matter as the underpinning agency for extraordinary sensitivity of biological membranes to electric fields.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Metareview: a survey of active matter reviews.The European physical journal. E, Soft matter · 2025Review
- Self-Organized Patterns in Non-Reciprocal Active Droplet Systems.Angewandte Chemie (International ed. in English) · 2024Article
- Learning protocols for the fast and efficient control of active matter.Nature communications · 2024Article
- Bio-Hybrid Magnetic Robots: From Bioengineering to Targeted Therapy.Bioengineering (Basel, Switzerland) · 2024Review
- Advances in tumor nanotechnology: theragnostic implications in tumors via targeting regulated cell death.Apoptosis : an international journal on programmed cell death · 2023Review
- Advances of medical nanorobots for future cancer treatments.Journal of hematology & oncology · 2023Review
- Active matter in space.NPJ microgravity · 2022Review
- Shape-Changing Particles: From Materials Design and Mechanisms to Implementation.Advanced materials (Deerfield Beach, Fla.) · 2022Review
- Shape Memory Alloy Helical Microrobots with Transformable Capability towards Vascular Occlusion Treatment.Research (Washington, D.C.) · 2022Article
- Mapping Viscoelastic Properties Using Helical Magnetic Nanopropellers.Transactions of the Indian National Academy of Engineering : an international journal of engineering and technology · 2021Article
- Non-equilibrium properties of an active nanoparticle in a harmonic potential.Nature communications · 2021Article
- Magnetic Resonance Guided Navigation of Untethered Microgrippers.Advanced healthcare materials · 2021Article
- Engineering microrobots for targeted cancer therapies from a medical perspective.Nature communications · 2020Review
- Medical Micro/Nanorobots in Precision Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Review
- Gastrointestinal-resident, shape-changing microdevices extend drug release in vivo.Science advances · 2020Article
- Effective interactions mediated between two permeable disks in an active fluid.Scientific reports · 2020Article
- Design of nematic liquid crystals to control microscale dynamics.Liquid crystals reviews · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Nanotherapies based on micelles, liposomes, polymersomes, nanocapsules, magnetic nanoparticles, and noble metal nanoparticles have been at the forefront of drug delivery in the past few decades. Some of these nanopharmaceuticals have been commercially applied to treat a wide range of diseases, from dry eye syndrome to cancer. However, the majority involve particles that are passive, meaning that they do not change shape, and they lack motility; the static features can limit their therapeutic efficacy. In this review, we take a critical look at an emerging field that seeks to utilize active matter for therapeutics. In this context, active matter can be broadly referred to as micro or nanosized constructs that energetically react with their environment or external fields and translate, rotate, vibrate or change shape. Essentially, the recent literature suggests that such particles could significantly augment present-day drug delivery, by enhancing transport and increasing permeability across anatomical barriers by transporting drugs within solid tumor microenvironments or disrupting cardiovascular plaque. We discuss examples of such particles and link the transport and permeability properties of active matter to potential therapeutic applications in the context of two major diseases, namely cancer and heart disease. We also discuss potential challenges, opportunities, and translational hurdles.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.