ArticleIndian journal of anaesthesia2020
A prospective 3 year study of clinical spectrum and outcome of dengue fever in ICU from a tertiary care hospital in North India.
Article in Indian journal of anaesthesia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Routine blood parameters of dengue infected children and adults. A meta-analysis.Pathogens and global health · 2023Pooled it
- Epidemiology of dengue in SAARC territory: a systematic review and meta-analysis.Parasites & vectors · 2022Pooled it
- Article
- Seroprevalence and clinical profile of dengue infection among acute febrile patients at a rural tertiary care hospital.World journal of virology · 2026Article
- Correlation of clinical, biochemical and molecular profile of dengue with disease severity.Virusdisease · 2025Article
- Dengue-induced cervical epidural haematoma in pregnancy.Indian journal of anaesthesia · 2022Article
- A modified Sequential Organ Failure Assessment score for dengue: development, evaluation and proposal for use in clinical trials.BMC infectious diseases · 2022Observational
- Article
- Severe Dengue: Lessons learnt from an observational study.Indian journal of anaesthesia · 2020Article
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3 authors.
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Abstract
BACKGROUND AND
aimsThe incidence of specific complications and adverse outcomes in dengue patients needing admission to intensive care units (ICU) may be quite variable in different regions of India presumably because of different strains of dengue virus or due to re infection.
methodsPatients admitted with acute febrile illness (AFI) with either positive IgM antibody or NS1 antigen for dengue were enrolled. Data were collected for 3 years (2015-2017). A total of 313 patients with acute febrile illness were admitted in the study period (2252 total ICU admissions). A total of 137 (43.76%) cases were serologically proven as dengue fever.
resultsMedian age (IQR) of study population was 36.0 (26.0-52.0) years. Liver (65.7%) was the main organ involved followed by acute kidney Injury (AKI) (18.6%). Dengue Shock Syndrome (DSS) was found in 18.6% of cases. Fifty-two patients died and the crude mortality was 38.0%. On multivariate analysis APACHE Score <10, thrombocytopenia, hepatic dysfunction, AKI and dengue shock syndrome (DSS) were associated with the risk of mortality.
conclusionThis study in ICU patients showed high mortality in relatively younger patients. Liver (in the form of raised Bilirubin) was the most common organ dysfunction. The need to recognise early warning signs for ICU admission is highlighted.
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