Evidence map›Paper›PMID 32346082›Full record

ArticleMucosal immunology2021

Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals.

Manon Nayrac, Mary Requena, Claire Loiseau, Michelle Cazabat, Bertrand Suc, Nicolas Carrere, Karl Barange, Laurent Alric, Guillaume Martin-Blondel, Jacques Izopet and 1 more

Registry-linked trialOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Mucosal immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02906137 (Altered Homing of T Lymphocytes to the Gut and Poor Immune Reconstitution of the Intestinal Mucosa in Treated HIV-infected Individuals), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02906137 nacompletednot on this map

Altered Homing of T Lymphocytes to the Gut and Poor Immune Reconstitution of the Intestinal Mucosa in Treated HIV-infected Individuals

TypeinterventionalSponsorANRS, Emerging Infectious DiseasesRan2017 to 2020Enrolled80ConditionsHIV-1 InfectionArmsPeripheral blood and intestinal biopsies will be collected
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Role of Th22 Cells in Human Viral Diseases.Frontiers in medicine · 2021
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Manon NayracINSERM, UMR1043, Toulouse, F-31300, France.
Mary RequenaCHU de Toulouse, Laboratoire de Virologie, Toulouse, F-31300, France.
Claire LoiseauINSERM, UMR1043, Toulouse, F-31300, France.
Michelle CazabatCHU de Toulouse, Laboratoire de Virologie, Toulouse, F-31300, France.
Bertrand SucUniversité Toulouse III Paul Sabatier, Toulouse, F-31300, France.
Nicolas CarrereUniversité Toulouse III Paul Sabatier, Toulouse, F-31300, France.
Karl BarangeCHU de Toulouse, Service d'Hépato-Gastro-Entérologie, Toulouse, F-31300, France.
Laurent AlricUniversité Toulouse III Paul Sabatier, Toulouse, F-31300, France.
Guillaume Martin-BlondelINSERM, UMR1043, Toulouse, F-31300, France.
Jacques IzopetINSERM, UMR1043, Toulouse, F-31300, France.
Pierre DelobelINSERM, UMR1043, Toulouse, F-31300, France. delobel.p@chu-toulouse.fr.ORCID http://orcid.org/0000-0002-2874-3581
Université Toulouse III - Paul Sabatier · FRCentre Hospitalier Universitaire de Toulouse · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut CD4

Indexed as

Antiretroviral Therapy, Highly ActiveBiomarkersChemokine CCL20Chemokines, CCChemotaxis, LeukocyteCytokinesHIV-1HIV InfectionsHost-Pathogen InteractionsHumansInflammation MediatorsIntestinal MucosaT-Lymphocyte SubsetsBiomarkersCCL20 protein, humanCCL28 protein, humanChemokine CCL20Chemokines, CCCytokinesInflammation Mediators

Identifiers

PMID32346082
OpenAlexW3020203637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.