ArticleScientific reports2020
Cuticular pheromones stimulate hygienic behavior in the honey bee (Apis mellifera).
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 40 citations in OpenAlex.
- Viral influence on chemical communication in eusocial insects: insights and emerging research priorities.Journal of insect science (Online) · 2026Review
- Biological costs and benefits of selective breeding for disease resistance using marker-assisted or field-based selective breeding in honey bees (Apis mellifera).Journal of economic entomology · 2026Article
- Evidence for virus-associated recapping behaviour in honey bees (Apis mellifera) with differential detection sensitivity between varroa-resistant and non-resistant colonies.Scientific reports · 2026Article
- The Weak Worker Hypothesis: a new framework for understanding division of labour in social insects.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Innate defense mechanisms against Nosema ceranae in hygienic honey bee (Apis mellifera) colonies.PloS one · 2026Article
- Altruistic disease signalling in ant colonies.Nature communications · 2025Article
- Varroa Volatiles Offer Chemical Cues to Honey Bees for Initial Parasitic Recognition.Biomolecules · 2025Article
- The effect of Israeli acute paralysis virus infection on honey bee brood care behavior.Scientific reports · 2024Article
- Detailed chemical analysis of honey bee (Apis mellifera) worker brood volatile profile from egg to emergence.PloS one · 2023Article
- Social Apoptosis in Varroa Mite Resistant Western Honey Bees (Apis mellifera).Journal of insect science (Online) · 2022Article
- Hygiene-Eliciting Brood Semiochemicals as a Tool for Assaying Honey Bee (Hymenoptera: Apidae) Colony Resistance to Varroa (Mesostigmata: Varroidae).Journal of insect science (Online) · 2021Article
- Suitability of drone olfactory sensitivity as a selection trait for Varroa-resistance in honeybees.Scientific reports · 2021Article
- Integrated Pest Management Control of Varroa destructor (Acari: Varroidae), the Most Damaging Pest of (Apis mellifera L. (Hymenoptera: Apidae)) Colonies.Journal of insect science (Online) · 2021Review
- Parallel evolution ofProceedings. Biological sciences · 2021Article
- Chemical detection triggers honey bee defense against a destructive parasitic threat.Nature chemical biology · 2021Article
- Advances and perspectives in selecting resistance traits against the parasitic mite Varroa destructor in honey bees.Genetics, selection, evolution : GSE · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The health of western honey bee (Apis mellifera) colonies is challenged by the parasitic mite Varroa destructor and the numerous harmful pathogens it vectors. Selective breeding for the naturally occurring social immune trait "hygienic behavior" has emerged as one sustainable approach to reducing the mites' impact on honey bees. To expand our understanding of hygienic triggers and improve hygienic selection tools, we tested the hypothesis that the cuticular compounds (Z)-10-tritriacontene and (Z)-6-pentadecene, previously associated with unhealthy honey bee brood and/or brood targeted for hygiene, are triggers of honey bee hygienic behavior independent of brood health. In support of our hypothesis, application of synthetic (Z)-10-tritriacontene and (Z)-6-pentadecene onto brood and brood cell caps significantly increased hygienic behavior compared to application of similarly structured hydrocarbon controls (Z)-16-dotriacontene and (Z)-7-pentadecene. Furthermore, we demonstrate a significant positive correlation between colony-level hygienic responses to (Z)-10-tritriacontene and the traditional freeze-killed brood assay for selection of hygienic honey bee stocks. These results confirm biological activity of (Z)-6-pentadecene and reveal (Z)-10-tritriacontene as a novel hygiene trigger. They also support development of improved tools for honey bee colony monitoring and hygienic selection, and thus may accelerate development of honey bee stocks with greater resistance to Varroa and associated pathogens.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.