Evidence map›Paper›PMID 32345986›Full record

ArticleScientific reports2020

Comprehensive characterization of mainstream marijuana and tobacco smoke.

Brian M Graves, Tyler J Johnson, Robert T Nishida, Ryan P Dias, Benjamin Savareear, James J Harynuk, Mohsen Kazemimanesh, Jason S Olfert, Adam M Boies

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
8.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 110 citations in OpenAlex.

  1. Trial
  2. Effects of Marijuana Use on Smokers Switching to E-Cigarettes in a Randomized Clinical Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. The AhR Is a Critical Regulator of the Pulmonary Response to Cannabis Smoke.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Cannabis concentrate vaping chemistry.Frontiers in toxicology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Brian M Graves *Department of Engineering, University of Cambridge, Trumpington Street, Cambridge, CB2 1PZ, United Kingdom.
Tyler J Johnson *Department of Engineering, University of Cambridge, Trumpington Street, Cambridge, CB2 1PZ, United Kingdom.
Robert T Nishida *Department of Engineering, University of Cambridge, Trumpington Street, Cambridge, CB2 1PZ, United Kingdom. rnishida@ualberta.ca.
Ryan P DiasDepartment of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada.
Benjamin SavareearDepartment of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada.
James J HarynukDepartment of Chemistry, University of Alberta, Edmonton, Alberta, T6G 2G2, Canada.
Mohsen KazemimaneshDepartment of Mechanical Engineering, University of Alberta, Edmonton, Alberta, T6G 1H9, Canada.
Jason S OlfertDepartment of Mechanical Engineering, University of Alberta, Edmonton, Alberta, T6G 1H9, Canada.
Adam M BoiesDepartment of Engineering, University of Cambridge, Trumpington Street, Cambridge, CB2 1PZ, United Kingdom. a.boies@eng.cam.ac.uk.
University of Alberta · CAUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent increases in marijuana use and legalization without adequate knowledge of the risks necessitate the characterization of the billions of nanoparticles contained in each puff of smoke. Tobacco smoke offers a benchmark given that it has been extensively studied. Tobacco and marijuana smoke particles are quantitatively similar in volatility, shape, density and number concentration, albeit with differences in size, total mass and chemical composition. Particles from marijuana smoke are on average 29% larger in mobility diameter than particles from tobacco smoke and contain 3.4× more total mass. New measurements of semi-volatile fractions determine over 97% of the mass and volume of the particles from either smoke source are comprised of semi-volatile compounds. For tobacco and marijuana smoke, respectively, 4350 and 2575 different compounds are detected, of which, 670 and 536 (231 in common) are tentatively identified, and of these, 173 and 110 different compounds (69 in common) are known to cause negative health effects through carcinogenic, mutagenic, teratogenic, or other toxic mechanisms. This study demonstrates striking similarities between marijuana and tobacco smoke in terms of their physical and chemical properties.

Indexed as

CannabisGas Chromatography-Mass SpectrometrySmokeVolatilizationSmoke

Identifiers

PMID32345986
PMCPMC7188852
OpenAlexW3018147373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.