Evidence map›Paper›PMID 32345958›Full record

ArticleCell death & disease2020

Chk1-mediated phosphorylation of Cdh1 promotes the SCF

Debjani Pal, Adrian E Torres, Benjamin R Stromberg, Abbey L Messina, Andrew S Dickson, Kuntal De, Belinda Willard, Monica Venere, Matthew K Summers

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. CDH1 Orchestrates Anabolic Events to Promote Cell Cycle Initiation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Debjani PalDepartment of Radiation Oncology, Arthur G James Comprehensive Cancer Center and Richard L. Solove Research Institute, The Ohio State University Medical Center, Columbus, OH, 43210, USA.
Adrian E Torres *Department of Radiation Oncology, Arthur G James Comprehensive Cancer Center and Richard L. Solove Research Institute, The Ohio State University Medical Center, Columbus, OH, 43210, USA.
Benjamin R Stromberg *Department of Radiation Oncology, Arthur G James Comprehensive Cancer Center and Richard L. Solove Research Institute, The Ohio State University Medical Center, Columbus, OH, 43210, USA.
Abbey L MessinaDepartment of Radiation Oncology, Arthur G James Comprehensive Cancer Center and Richard L. Solove Research Institute, The Ohio State University Medical Center, Columbus, OH, 43210, USA.
Andrew S DicksonDepartment of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
Kuntal DeDepartment of Radiation Oncology, Arthur G James Comprehensive Cancer Center and Richard L. Solove Research Institute, The Ohio State University Medical Center, Columbus, OH, 43210, USA.
Belinda WillardProteomics and Metabolomics Core, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
Monica VenereDepartment of Radiation Oncology, Arthur G James Comprehensive Cancer Center and Richard L. Solove Research Institute, The Ohio State University Medical Center, Columbus, OH, 43210, USA.
Matthew K SummersDepartment of Radiation Oncology, Arthur G James Comprehensive Cancer Center and Richard L. Solove Research Institute, The Ohio State University Medical Center, Columbus, OH, 43210, USA. matthew.summers@osumc.edu.
The Ohio State University Wexner Medical Center · USCleveland Clinic Lerner College of Medicine · USThe Ohio State University · USThe Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
Mechanisms of Spindle Assembly Checkpoint SilencingR01GM108743 · NIGMS · OHIO STATE UNIVERSITY · PI SUMMERS, MATTHEW K · 2014 to 2017
$1.2M
Dissecting functional interplay of deubiquitinases and the cell cycle machineryR01GM112895 · NIGMS · OHIO STATE UNIVERSITY · PI SUMMERS, MATTHEW K · 2015 to 2018
$1.2M
LTQ-Orbitrap Velos instrumentS10RR031537 · NCRR · CLEVELAND CLINIC LERNER COM-CWRU · PI WILLARD, BELINDA BELLE · 2011 to 2011
$600k
Targeting epigenetic remodeling factors to radiosensitize glioblastomaR03CA227206 · NCI · OHIO STATE UNIVERSITY · PI VENERE, MONICA · 2019 to 2020
$156k
NCI NIH HHS P30 CA016058NCI NIH HHS R03 CA227206NCRR NIH HHS S10 RR031537NIGMS NIH HHS R01 GM108743NIGMS NIH HHS R01 GM112895
6 · The paper itself

Abstract

APC/C

Indexed as

Cdh1 ProteinsCell Cycle ProteinsCheckpoint Kinase 1HeLa CellsHumansPhosphorylationS PhaseTransfectionUbiquitinCdh1 ProteinsCell Cycle ProteinsCheckpoint Kinase 1Ubiquitin

Identifiers

PMID32345958
PMCPMC7188793
OpenAlexW3017541162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.