Evidence map›Paper›PMID 32345709›Full record

ArticleCMAJ open

Emergency department use by pregnant women in Ontario: a retrospective population-based cohort study.

Catherine E Varner, Alison L Park, Darby Little, Joel G Ray

Open access · diamondAbstract read
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  6. Observational
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  15. Diagnosis and management of early pregnancy loss.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024
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  17. Diagnosis and treatment of hyperemesis gravidarum.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Catherine E VarnerSchwartz/Reisman Emergency Medicine Institute (Varner, Little) and Department of Family and Community Medicine (Varner), University of Toronto; University of Toronto (Varner, Little), Sinai Health System; ICES (Park, Ray); Keenan Research Centre (Ray), Li Ka Shing Knowledge Institute and Department of Obstetrics and Gynecology (Ray), St. Michael's Hospital, Toronto, Ont. catherine.varner@sinaihealthsystem.ca.
Alison L ParkSchwartz/Reisman Emergency Medicine Institute (Varner, Little) and Department of Family and Community Medicine (Varner), University of Toronto; University of Toronto (Varner, Little), Sinai Health System; ICES (Park, Ray); Keenan Research Centre (Ray), Li Ka Shing Knowledge Institute and Department of Obstetrics and Gynecology (Ray), St. Michael's Hospital, Toronto, Ont.
Darby LittleSchwartz/Reisman Emergency Medicine Institute (Varner, Little) and Department of Family and Community Medicine (Varner), University of Toronto; University of Toronto (Varner, Little), Sinai Health System; ICES (Park, Ray); Keenan Research Centre (Ray), Li Ka Shing Knowledge Institute and Department of Obstetrics and Gynecology (Ray), St. Michael's Hospital, Toronto, Ont.
Joel G RaySchwartz/Reisman Emergency Medicine Institute (Varner, Little) and Department of Family and Community Medicine (Varner), University of Toronto; University of Toronto (Varner, Little), Sinai Health System; ICES (Park, Ray); Keenan Research Centre (Ray), Li Ka Shing Knowledge Institute and Department of Obstetrics and Gynecology (Ray), St. Michael's Hospital, Toronto, Ont.
Schwartz/Reisman Emergency Medicine Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeripregnancy emergency department use may be common, but data specific to health care systems like that in Canada are lacking. As prior research was limited to livebirths, omitting pregnancies ending in miscarriage or induced abortion, the current study quantified and characterized emergency department use among women in Ontario with a recognized pregnancy.

methodsThis retrospective population-based cohort study included all recognized pregnancies among Ontario residents aged 10-55 years with an estimated date of conception between Apr. 1, 2002, and Mar. 31, 2017. We defined peripregnancy emergency department use as any emergency department visit during pregnancy or within 42 days after pregnancy. We used modified Poisson regression with a robust error variance to generate relative risks (RRs) and 95% confidence intervals (CIs) for the outcome of any peripregnancy emergency department use in association with maternal age, parity, residential income quintile, location of residence, immigrant status, antenatal care provider and number of comorbidities within 120 days before the clinical start of the pregnancy (expressed as total number of Aggregated Diagnosis Groups [ADGs] obtained with the Johns Hopkins Adjusted Clinical Group System). All RRs, except for number of comorbidities, were further adjusted for number of ADGs.

resultsPeripregnancy emergency department use occurred in 1 075 991 (39.4%) of 2 728 236 recognized pregnancies, including 35.8% of livebirths, 47.3% of stillbirths, 73.7% of miscarriages and 84.8% of threatened abortions. A peripregnancy emergency department visit was more likely among women who were less than 25 years of age (adjusted RR 1.16, 95% CI 1.16-1.17), were nulliparous (adjusted RR 1.13, 95% CI 1.13-1.13), resided in the lowest income quintile area (adjusted RR 1.16, 95% CI 1.15-1.16) or in a rural area (adjusted RR 1.50, 95% CI 1.50-1.51), were Canadian-born (adjusted RR 1.22, 95% CI 1.22-1.23), were not seen by an obstetrician (adjusted RR 1.66, 95% CI 1.54-1.80) or had a greater number of ADGs. Emergency department use peaked in the first trimester and in the first week postpartum. Compared to women residing in urban areas, those residing in rural areas had an odds ratio (OR) of 3.44 (95% CI 3.39-3.49) for 3 or more emergency department visits. Women with 3-4 (OR 1.99, 95% CI 1.97-2.01), 5-6 (OR 3.55, 95% CI 3.49-3.61), or 7 or more (OR 7.59, 95% CI 7.39-7.78) prepregnancy comorbidities were more likely to have 3 or more peripregnancy emergency department visits than were those with 2 or fewer comorbidities.

interpretationPeripregnancy emergency department use occurred in nearly 40% of pregnancies, notably in the first trimester and early in the postpartum period. Efforts are needed to streamline rapid access to ambulatory obstetric care during these peak periods, when women are susceptible to miscarriage or a complication after a livebirth.

Indexed as

Pregnant PeopleAdolescentAdultChildEmergency Medical ServicesEmergency Service, HospitalFemaleHumansMiddle AgedOdds RatioOntarioPopulation SurveillancePregnancyRetrospective StudiesYoung Adult

Identifiers

PMID32345709
PMCPMC7207029
OpenAlexW3020248971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.