Evidence map›Paper›PMID 32345706›Full record

ArticleCMAJ open

Deprivation and mortality related to pediatric respiratory tract infection: a cohort study in 3 high-income jurisdictions.

Maximiliane L Verfürden, Tiffany Fitzpatrick, Laura Holder, Ania Zylbersztejn, Laura Rosella, Ruth Gilbert, Astrid Guttmann, Pia Hardelid

Open access · diamondAbstract read
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Temporal clustering of neuroblastic tumours in children and young adults from Scotland.Environmental health : a global access science source · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Maximiliane L VerfürdenPopulation, Policy and Practice Programme (Verfürden, Zylbersztejn, Gilbert, Hardelid), UCL Great Ormond Street Institute of Child Health, London, UK; Dalla Lana School of Public Health (Fitzpatrick, Rosella, Guttmann) and Department of Paediatrics (Guttmann), University of Toronto; Child Health Evaluative Sciences (Fitzpatrick, Guttmann) and Division of Paediatric Medicine (Guttmann), The Hospital for Sick Children; ICES (Holder, Rosella, Guttmann), Toronto, Ont. m.verfuerden@ucl.ac.uk.
Tiffany FitzpatrickPopulation, Policy and Practice Programme (Verfürden, Zylbersztejn, Gilbert, Hardelid), UCL Great Ormond Street Institute of Child Health, London, UK; Dalla Lana School of Public Health (Fitzpatrick, Rosella, Guttmann) and Department of Paediatrics (Guttmann), University of Toronto; Child Health Evaluative Sciences (Fitzpatrick, Guttmann) and Division of Paediatric Medicine (Guttmann), The Hospital for Sick Children; ICES (Holder, Rosella, Guttmann), Toronto, Ont.
Laura HolderPopulation, Policy and Practice Programme (Verfürden, Zylbersztejn, Gilbert, Hardelid), UCL Great Ormond Street Institute of Child Health, London, UK; Dalla Lana School of Public Health (Fitzpatrick, Rosella, Guttmann) and Department of Paediatrics (Guttmann), University of Toronto; Child Health Evaluative Sciences (Fitzpatrick, Guttmann) and Division of Paediatric Medicine (Guttmann), The Hospital for Sick Children; ICES (Holder, Rosella, Guttmann), Toronto, Ont.
Ania ZylbersztejnPopulation, Policy and Practice Programme (Verfürden, Zylbersztejn, Gilbert, Hardelid), UCL Great Ormond Street Institute of Child Health, London, UK; Dalla Lana School of Public Health (Fitzpatrick, Rosella, Guttmann) and Department of Paediatrics (Guttmann), University of Toronto; Child Health Evaluative Sciences (Fitzpatrick, Guttmann) and Division of Paediatric Medicine (Guttmann), The Hospital for Sick Children; ICES (Holder, Rosella, Guttmann), Toronto, Ont.
Laura RosellaPopulation, Policy and Practice Programme (Verfürden, Zylbersztejn, Gilbert, Hardelid), UCL Great Ormond Street Institute of Child Health, London, UK; Dalla Lana School of Public Health (Fitzpatrick, Rosella, Guttmann) and Department of Paediatrics (Guttmann), University of Toronto; Child Health Evaluative Sciences (Fitzpatrick, Guttmann) and Division of Paediatric Medicine (Guttmann), The Hospital for Sick Children; ICES (Holder, Rosella, Guttmann), Toronto, Ont.
Ruth GilbertPopulation, Policy and Practice Programme (Verfürden, Zylbersztejn, Gilbert, Hardelid), UCL Great Ormond Street Institute of Child Health, London, UK; Dalla Lana School of Public Health (Fitzpatrick, Rosella, Guttmann) and Department of Paediatrics (Guttmann), University of Toronto; Child Health Evaluative Sciences (Fitzpatrick, Guttmann) and Division of Paediatric Medicine (Guttmann), The Hospital for Sick Children; ICES (Holder, Rosella, Guttmann), Toronto, Ont.
Astrid GuttmannPopulation, Policy and Practice Programme (Verfürden, Zylbersztejn, Gilbert, Hardelid), UCL Great Ormond Street Institute of Child Health, London, UK; Dalla Lana School of Public Health (Fitzpatrick, Rosella, Guttmann) and Department of Paediatrics (Guttmann), University of Toronto; Child Health Evaluative Sciences (Fitzpatrick, Guttmann) and Division of Paediatric Medicine (Guttmann), The Hospital for Sick Children; ICES (Holder, Rosella, Guttmann), Toronto, Ont.
Pia HardelidPopulation, Policy and Practice Programme (Verfürden, Zylbersztejn, Gilbert, Hardelid), UCL Great Ormond Street Institute of Child Health, London, UK; Dalla Lana School of Public Health (Fitzpatrick, Rosella, Guttmann) and Department of Paediatrics (Guttmann), University of Toronto; Child Health Evaluative Sciences (Fitzpatrick, Guttmann) and Division of Paediatric Medicine (Guttmann), The Hospital for Sick Children; ICES (Holder, Rosella, Guttmann), Toronto, Ont.
Great Ormond Street Hospital · GBUniversity College London · GBInstitut Guttmann · ES

Funding

CIHR APR 126 377Department of Health
6 · The paper itself

Abstract

backgroundDeaths from respiratory tract infections (RTIs) in children are preventable through timely access to public health and medical interventions. We aimed to assess whether socioeconomic disparities in mortality related to pediatric RTI persisted after accounting for health status at birth.

methodsWe compared the prevalence of and risk factors for RTI-related death in singletons aged 28 days to 4 years across Ontario (Canada), Scotland and England (jurisdictions with universal health care) using linked administrative data for 2003-2013. We estimated rates of RTI-related mortality for children living in deprived areas and those born to teenage girls; we estimated both crude rates and those adjusted for health status at birth.

resultsA total of 1 299 240 (Ontario), 547 556 (Scotland) and 3 910 401 (England) children were included in the study. Across all jurisdictions, children born in the most deprived areas experienced the highest rates of RTI-related mortality. After adjustment for high-risk chronic conditions and prematurity, we observed differences in mortality according to area-level deprivation in Ontario and England but not in Scotland. In Ontario, teenage motherhood was also an independent risk factor for RTI-related mortality.

interpretationSocioeconomic disparities played a substantial role in child mortality related to RTI in all 3 jurisdictions. Context-specific investigations around the mechanisms of this increased risk and development of programs to address socioeconomic disparities are needed.

Indexed as

Health Status DisparitiesAdultChildChild, PreschoolCohort StudiesFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMortalityOntarioProportional Hazards ModelsRespiratory Tract InfectionsRisk FactorsSocial Class

Identifiers

PMID32345706
PMCPMC7207030
OpenAlexW3019080732

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.