Evidence map›Paper›PMID 32345624›Full record

ArticleJournal for immunotherapy of cancer2020

Predictive value of integrated

Yukihiro Umeda, Miwa Morikawa, Masaki Anzai, Shingo Ameshima, Maiko Kadowaki, Yuko Waseda, Hiroko Shigemi, Tetsuya Tsujikawa, Yasushi Kiyono, Hidehiko Okazawa and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal for immunotherapy of cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. [European journal of nuclear medicine and molecular imaging · 2022
    Trial
  3. Review
  4. Review
  5. FDG PET/CT Imaging 1 Week after a Single Dose of Pembrolizumab Predicts Treatment Response in Patients with Advanced Melanoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  6. Article
  7. Immune checkpoint inhibition: a future guided by radiology.The British journal of radiology · 2023
    Review
  8. MRI techniques for immunotherapy monitoring.Journal for immunotherapy of cancer · 2022
    Review
  9. Prospective assessment usingScientific reports · 2022
    Article
  10. CD8-Targeted PET Imaging of Tumor-Infiltrating T Cells in Patients with Cancer: A Phase I First-in-Humans Study ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  11. Article
  12. Review
  13. Review
  14. Predictive value of 3'-deoxy-3'-Journal for immunotherapy of cancer · 2021
    Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yukihiro UmedaThird Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan umeda@u-fukui.ac.jp.ORCID 0000-0002-9826-6856
Miwa MorikawaThird Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
Masaki AnzaiThird Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
Shingo AmeshimaDepartment of Internal Medicine, Sakai Municipal Mikuni Hospital, Fukui, Japan.
Maiko KadowakiThird Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
Yuko WasedaThird Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
Hiroko ShigemiThird Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
Tetsuya TsujikawaBiomedical Imaging Research Center, University of Fukui, Fukui, Japan.
Yasushi KiyonoBiomedical Imaging Research Center, University of Fukui, Fukui, Japan.
Hidehiko OkazawaBiomedical Imaging Research Center, University of Fukui, Fukui, Japan.ORCID 0000-0001-7046-3383
Tamotsu IshizukaThird Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
University of Fukui · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe early response to treatment with immune-checkpoint inhibitors is difficult to evaluate. We determined whether changes in integrated [

methodsTwenty-five patients with previously treated NSCLC were enrolled prospectively and underwent

resultsThe disease control rate was 64%. Patients with non-progressive disease (non-PD) had significantly decreased TLG, increased ADC

conclusionsA combination of ΔTLG and ΔADC TRIAL REGISTRATION NUMBER: UMIN 000020707.

Indexed as

AgedAged, 80 and overCarcinoma, Non-Small-Cell LungFemaleFluorodeoxyglucose F18HumansLung NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedNivolumabPositron Emission Tomography Computed TomographyTreatment OutcomeFluorodeoxyglucose F18NivolumabMRInuclear medicineoncologyPET

Identifiers

PMID32345624
PMCPMC7213911
OpenAlexW3019034382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.