Evidence map›Paper›PMID 32345621›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2020

Comparative Pharmacokinetics of Δ

Alexa Torrens, Valentina Vozella, Hannah Huff, Brandon McNeil, Faizy Ahmed, Andrea Ghidini, Stephen V Mahler, Marilyn A Huestis, Aditi Das, Daniele Piomelli

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 83 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Prenatal Cannabis and Tobacco: Studies in Animal Models.Advances in experimental medicine and biology · 2026
    Review
  6. Cannabinoids rescue migraine symptoms caused by central CGRP administration in mice.Cephalalgia : an international journal of headache · 2025
    Article
  7. Adolescent exposure to Δ9-tetrahydrocannabinol impairs testicular function in young adult male mice.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Article
  8. Article
  9. Article
  10. Neural basis of adolescent THC-induced potentiation of opioid responses later in life.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  11. Article
  12. ∆Tissue engineering and regenerative medicine · 2025
    Article
  13. Article
  14. The Pharmacokinetics of ΔAnimals : an open access journal from MDPI · 2024
    Article
  15. ΔThe Journal of pharmacology and experimental therapeutics · 2024
    Article
  16. Cells and Molecules Underpinning Cannabis-Related Variations in Cortical Thickness during Adolescence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Alexa TorrensDepartments of Anatomy and Neurobiology (A.T., V.V., B.M., F.A., A.G., D.P.), Neurobiology and Behavior (S.V.M.), Biological Chemistry (D.P.), and Pharmaceutical Sciences (D.P.), University of California, Irvine, California; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois (H.H., A.D.); Dipartimento di Scienza degli Alimenti e del Farmaco, Università degli Studi di Parma, Parma Italy (A.G.); and Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, Pennsylvania (M.A.H.).
Valentina VozellaDepartments of Anatomy and Neurobiology (A.T., V.V., B.M., F.A., A.G., D.P.), Neurobiology and Behavior (S.V.M.), Biological Chemistry (D.P.), and Pharmaceutical Sciences (D.P.), University of California, Irvine, California; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois (H.H., A.D.); Dipartimento di Scienza degli Alimenti e del Farmaco, Università degli Studi di Parma, Parma Italy (A.G.); and Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, Pennsylvania (M.A.H.).
Hannah HuffDepartments of Anatomy and Neurobiology (A.T., V.V., B.M., F.A., A.G., D.P.), Neurobiology and Behavior (S.V.M.), Biological Chemistry (D.P.), and Pharmaceutical Sciences (D.P.), University of California, Irvine, California; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois (H.H., A.D.); Dipartimento di Scienza degli Alimenti e del Farmaco, Università degli Studi di Parma, Parma Italy (A.G.); and Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, Pennsylvania (M.A.H.).
Brandon McNeilDepartments of Anatomy and Neurobiology (A.T., V.V., B.M., F.A., A.G., D.P.), Neurobiology and Behavior (S.V.M.), Biological Chemistry (D.P.), and Pharmaceutical Sciences (D.P.), University of California, Irvine, California; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois (H.H., A.D.); Dipartimento di Scienza degli Alimenti e del Farmaco, Università degli Studi di Parma, Parma Italy (A.G.); and Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, Pennsylvania (M.A.H.).
Faizy AhmedDepartments of Anatomy and Neurobiology (A.T., V.V., B.M., F.A., A.G., D.P.), Neurobiology and Behavior (S.V.M.), Biological Chemistry (D.P.), and Pharmaceutical Sciences (D.P.), University of California, Irvine, California; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois (H.H., A.D.); Dipartimento di Scienza degli Alimenti e del Farmaco, Università degli Studi di Parma, Parma Italy (A.G.); and Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, Pennsylvania (M.A.H.).
Andrea GhidiniDepartments of Anatomy and Neurobiology (A.T., V.V., B.M., F.A., A.G., D.P.), Neurobiology and Behavior (S.V.M.), Biological Chemistry (D.P.), and Pharmaceutical Sciences (D.P.), University of California, Irvine, California; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois (H.H., A.D.); Dipartimento di Scienza degli Alimenti e del Farmaco, Università degli Studi di Parma, Parma Italy (A.G.); and Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, Pennsylvania (M.A.H.).
Stephen V MahlerDepartments of Anatomy and Neurobiology (A.T., V.V., B.M., F.A., A.G., D.P.), Neurobiology and Behavior (S.V.M.), Biological Chemistry (D.P.), and Pharmaceutical Sciences (D.P.), University of California, Irvine, California; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois (H.H., A.D.); Dipartimento di Scienza degli Alimenti e del Farmaco, Università degli Studi di Parma, Parma Italy (A.G.); and Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, Pennsylvania (M.A.H.).ORCID 0000-0002-8698-0905
Marilyn A HuestisDepartments of Anatomy and Neurobiology (A.T., V.V., B.M., F.A., A.G., D.P.), Neurobiology and Behavior (S.V.M.), Biological Chemistry (D.P.), and Pharmaceutical Sciences (D.P.), University of California, Irvine, California; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois (H.H., A.D.); Dipartimento di Scienza degli Alimenti e del Farmaco, Università degli Studi di Parma, Parma Italy (A.G.); and Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, Pennsylvania (M.A.H.).
Aditi DasDepartments of Anatomy and Neurobiology (A.T., V.V., B.M., F.A., A.G., D.P.), Neurobiology and Behavior (S.V.M.), Biological Chemistry (D.P.), and Pharmaceutical Sciences (D.P.), University of California, Irvine, California; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois (H.H., A.D.); Dipartimento di Scienza degli Alimenti e del Farmaco, Università degli Studi di Parma, Parma Italy (A.G.); and Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, Pennsylvania (M.A.H.).
Daniele PiomelliDepartments of Anatomy and Neurobiology (A.T., V.V., B.M., F.A., A.G., D.P.), Neurobiology and Behavior (S.V.M.), Biological Chemistry (D.P.), and Pharmaceutical Sciences (D.P.), University of California, Irvine, California; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois (H.H., A.D.); Dipartimento di Scienza degli Alimenti e del Farmaco, Università degli Studi di Parma, Parma Italy (A.G.); and Institute of Emerging Health Professions, Thomas Jefferson University, Philadelphia, Pennsylvania (M.A.H.) piomelli@hs.uci.edu.
University of Parma · IT

Funding

Impact of Cannabinoid Across the Lifespan (ICAL)P50DA044118 · NIDA · UNIVERSITY OF CALIFORNIA-IRVINE · PI Stephen Vincent Mahler · 2018 to 2026
$18.2M
Biochemical Mechanism of Eicosanoid Synthesizing EnzymesR01GM115584 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI DAS, ADITI · 2017 to 2022
$1.7M
NIDA NIH HHS P50 DA044118NIGMS NIH HHS R01 GM115584
6 · The paper itself

Abstract

We investigated the pharmacokinetic properties of Δ

Indexed as

AgingAnimalsATP-Binding Cassette TransportersClaudin-5DronabinolGene Expression RegulationMaleMiceRNA, MessengerTissue DistributionATP-Binding Cassette TransportersClaudin-5DronabinolRNA, Messenger

Identifiers

PMID32345621
PMCPMC7318794
OpenAlexW3020339135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.