Evidence map›Paper›PMID 32345277›Full record

ArticleBMC public health2020

Multimorbidity and quality of life after blast-related injury among US military personnel: a cluster analysis of retrospective data.

Andrew J MacGregor, James M Zouris, Jessica R Watrous, Cameron T McCabe, Amber L Dougherty, Michael R Galarneau, John J Fraser

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Differences in quality-of-life scores across injury categories by mental health status among injured U.S. military service members and veterans.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  9. Article
  10. Otologic Injuries Secondary to Explosive Attack.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  11. Article
  12. Article
  13. Symptom profiles following combat injury and long-term quality of life: a latent class analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
    Article
  14. Long-Term Outcomes of Service Women Injured on Combat Deployment.International journal of environmental research and public health · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Andrew J MacGregorMedical Modeling, Simulation, and Mission Support Department, Naval Health Research Center, 140 Sylvester Road, San Diego, CA, 92106, USA. andrewmacgregor@protonmail.com.
James M ZourisMedical Modeling, Simulation, and Mission Support Department, Naval Health Research Center, 140 Sylvester Road, San Diego, CA, 92106, USA.
Jessica R WatrousMedical Modeling, Simulation, and Mission Support Department, Naval Health Research Center, 140 Sylvester Road, San Diego, CA, 92106, USA.
Cameron T McCabeMedical Modeling, Simulation, and Mission Support Department, Naval Health Research Center, 140 Sylvester Road, San Diego, CA, 92106, USA.
Amber L DoughertyMedical Modeling, Simulation, and Mission Support Department, Naval Health Research Center, 140 Sylvester Road, San Diego, CA, 92106, USA.
Michael R GalarneauMedical Modeling, Simulation, and Mission Support Department, Naval Health Research Center, 140 Sylvester Road, San Diego, CA, 92106, USA.
John J FraserWarfighter Performance Department, Naval Health Research Center, 140 Sylvester Road, San Diego, CA, 92106, USA.
Naval Health Research Center · USLeidos (United States) · US

Funding

Bureau of Medicine and Surgery WW00089 Work Unit 60808
6 · The paper itself

Abstract

backgroundBlast injury emerged as a primary source of morbidity among US military personnel during the recent conflicts in Iraq and Afghanistan, and led to an array of adverse health outcomes. Multimorbidity, or the presence of two or more medical conditions in an individual, can complicate treatment strategies. To date, there is minimal research on the impact of multimorbidity on long-term patient-reported outcomes. We aimed to define multimorbidity patterns in a population of blast-injured military personnel, and to examine these patterns in relation to long-term quality of life (QOL).

methodsA total of 1972 US military personnel who sustained a blast-related injury during military operations in Iraq and Afghanistan were identified from clinical records. Electronic health databases were used to identify medical diagnoses within the first year postinjury, and QOL was measured with a web-based assessment. Hierarchical cluster analysis methods using Ward's minimum variance were employed to identify clusters with related medical diagnosis categories. Duncan's multiple range test was used to group clusters into domains by QOL.

resultsFive distinct clusters were identified and grouped into three QOL domains. The lowest QOL domain contained one cluster with a clinical triad reflecting musculoskeletal pain, concussion, and mental health morbidity. The middle QOL domain had two clusters, one with concussion/anxiety predominating and the other with polytrauma. The highest QOL domain had two clusters with little multimorbidity aside from musculoskeletal pain.

conclusionsThe present study described blast-related injury profiles with varying QOL levels that may indicate the need for integrated health services. Implications exist for current multidisciplinary care of wounded active duty and veteran service members, and future research should determine whether multimorbidity denotes distinct post-blast injury syndromes.

Indexed as

MultimorbidityQuality of LifeAdultAfghan Campaign 2001-Blast InjuriesBrain ConcussionCluster AnalysisFemaleHumansIraq War, 2003-2011MaleMental DisordersMiddle AgedMilitary PersonnelMusculoskeletal PainOccupational InjuriesBlast injuryCombatDeploymentMilitaryMultimorbidityQuality of life

Identifiers

PMID32345277
PMCPMC7189580
OpenAlexW3020811676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.