ArticleBMC pregnancy and childbirth2020
Early maternal weight gain as a risk factor for SGA in pregnancies with hyperemesis gravidarum: a 15-year hospital cohort study.
Article in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
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11 citing papers in PubMed, 36 citations in OpenAlex.
- Watermelon and dietary advice compared to dietary advice alone following hospitalization for hyperemesis gravidarum: a randomized controlled trial.BMC pregnancy and childbirth · 2023Trial
- Association between nausea and vomiting during pregnancy and adverse pregnancy outcomes: findings from the nuMoM2b study.Archives of gynecology and obstetrics · 2025Article
- Hyperemesis gravidarum and the risk of offspring morbidity: a longitudinal cohort study.European journal of pediatrics · 2024Article
- The IRIS clinic: A Protocol for a mixed-methods study evaluating the management of Hyperemesis Gravidarum.Contemporary clinical trials communications · 2024Article
- Risk Factors for Infusions, Emergency Room Visits and Hospitalizations for Hyperemesis Gravidarum: New Data and Literature Review.International journal of women's health · 2024Article
- Rates of maternal weight gain over the course of pregnancy and offspring risk of neurodevelopmental disorders.BMC medicine · 2023Article
- Patterns of Use and Self-reported Effectiveness of Cannabis for Hyperemesis Gravidarum.Geburtshilfe und Frauenheilkunde · 2022Article
- Lack of catch-up in weight gain may intermediate between pregnancies with hyperemesis gravidarum and reduced fetal growth: the Japan Environment and Children's Study.BMC pregnancy and childbirth · 2022Article
- Association between body mass index in the first half of pregnancy and gestational diabetes: A systematic review.SAGE open medicine · 2022Review
- Correction to: Early maternal weight gain as a risk factor for SGA in pregnancies with hyperemesis gravidarum: a 15-year hospital cohort study.BMC pregnancy and childbirth · 2020Article
- Determinants of weight gain in pregnant women with hyperemesis gravidarum in Dire Dawa administration, Eastern Ethiopia: An unmatched case-control study.Women's health (London, England)Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInadequate maternal weight gain increases the risk of small-for-gestational age (SGA) infants. Women with hyperemesis gravidarum (HG) are at risk of significant early pregnancy weight loss and insufficient total pregnancy weight gain. Recent studies have implied that weight gain during the first half of pregnancy is more crucial to pregnancy outcome than total weight gain. The aim of this study was to investigate whether not regaining prepregnancy weight by 13-18 weeks of gestation contributed to not reaching minimum body mass index (BMI)-specific total pregnancy weight gain and influenced the risk of SGA outcome in HG pregnancies.
methodsIn this retrospective 15-year cohort (2002-2016) of women hospitalized due to hyperemesis gravidarum, we reviewed individual patient hospital files and corresponding outpatient maternity records to collect prepregnancy BMI and weight, pregnancy weight gain (spanning 3-week intervals), delivery weight and foetal outcomes. BMI and total pregnancy weight gain goals were categorized according to the Institute of Medicine (IOM) 2009 guidelines: BMI < 18,5 kg/m
resultsOut of 892 women hospitalized for HG during 2002-2016, 784 had a pregnancy lasting > 24 weeks, of which 746 were singleton pregnancies with follow-up until delivery. Among these women, 42 were classified as underweight, 514 as normal weight, 230 as overweight and 102 as obese before pregnancy. Not regaining prepregnancy weight by week 13-18 was an independent predictor of inadequate total gestational weight gain with an OR of 7.05 (95% CI 4.24-11.71) and an independent predictor for SGA outcome with an OR of 2.66 (95% CI 1.11-6.34), even when adjusted for total pregnancy weight gain, prepregnancy BMI, parity, age and smoking status.
conclusionInadequate total maternal weight gain and not regaining prepregnancy weight by week 13-18 may be considered independent risk factors for delivering a baby that is small for gestational age in pregnancies with hyperemesis gravidarum. Achieving adequate weight gain during the first trimester in HG pregnancies is important for the foetal outcome, underscoring the importance of nutritional treatment during this period.
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