Evidence map›Paper›PMID 32345161›Full record

ReviewProceedings. Biological sciences2020

Developmental programming of mitochondrial biology: a conceptual framework and review.

Lauren E Gyllenhammer, Sonja Entringer, Claudia Buss, Pathik D Wadhwa

Open access · bronzeAbstract readReview
In one paragraph

Review in Proceedings. Biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 70 citations in OpenAlex.

  1. A transient mitochondrial switch underlies long lasting effects of adolescent cannabis.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
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  5. Review
  6. Article
  7. Cocoa Shell Extract Restores Redox Balance in Developmental Hypertension in Male Rats: Roles of Nrf2, SOD2 and p-eNOS.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. NNanotoxicology · 2023
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Lauren E GyllenhammerDevelopment, Health and Disease Research Program, School of Medicine, Irvine, CA, USA.
Sonja EntringerDevelopment, Health and Disease Research Program, School of Medicine, Irvine, CA, USA.
Claudia BussDevelopment, Health and Disease Research Program, School of Medicine, Irvine, CA, USA.
Pathik D WadhwaDevelopment, Health and Disease Research Program, School of Medicine, Irvine, CA, USA.
University of California, Irvine · US

Funding

Intergenerational Effects of Maternal Childhood Trauma on the Fetal BrainR01MH105538 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI BUSS, CLAUDIA, FAIR, DAMIEN A · 2015 to 2019
$3.5M
EMA Assessment of Biobehavioral Processes in Human PregnancyR01HD060628 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI WADHWA, PATHIK D · 2010 to 2014
$3.4M
Social Disadvantage and Fetal Programming of Newborn-Infant Telomere BiologyR01AG050455 · NIA · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI EPEL, ELISSA S., SIMHAN, HYAGRIV N · 2016 to 2020
$3.0M
Synergistic effect of maternal insulin-resistance and cortisol in pregnancy on fetal programming of child mitochondrial function and obesity riskR00HD097302 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI GYLLENHAMMER, LAUREN ELIZABETH · 2022 to 2024
$744k
Synergistic effect of maternal insulin-resistance and cortisol in pregnancy on fetal programming of child mitochondrial function and obesity riskK99HD097302 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI GYLLENHAMMER, LAUREN ELIZABETH · 2019 to 2021
$272k
NIA NIH HHS R01 AG050455NICHD NIH HHS K99 HD097302NICHD NIH HHS R00 HD097302NICHD NIH HHS R01 HD060628NIMH NIH HHS R01 MH105538
6 · The paper itself

Abstract

Research on mechanisms underlying the phenomenon of developmental programming of health and disease has focused primarily on processes that are specific to cell types, organs and phenotypes of interest. However, the observation that exposure to suboptimal or adverse developmental conditions

Indexed as

Adaptation, PhysiologicalBiological EvolutionMitochondriaAnimalsHumansbioenergeticsdevelopmental programmingfetal programmingmaternal–fetal–placental biologymitochondria

Identifiers

PMID32345161
PMCPMC7282904
OpenAlexW3020094969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.