Evidence map›Paper›PMID 32345105›Full record

ArticleJournal of dental research2020

Establishment and Stability of the Murine Oral Microbiome.

L Abusleme, H O'Gorman, N Dutzan, T Greenwell-Wild, N M Moutsopoulos

Abstract read
In one paragraph

Article in Journal of dental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Transcription-based comparison ofMicrobiology spectrum · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Oral dysbiosis initiates periodontal disease in experimental kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Oral Microbiome UsingMedicina (Kaunas, Lithuania) · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

L AbuslemeLaboratory of Oral Microbiology, Faculty of Dentistry, University of Chile, Santiago, Chile.ORCID 0000-0002-7210-1236
H O'GormanNational Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.
N DutzanLaboratory of Oral Microbiology, Faculty of Dentistry, University of Chile, Santiago, Chile.ORCID 0000-0001-8343-0214
T Greenwell-WildNational Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.
N M MoutsopoulosNational Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.

Funding

Mechanisms of Chronic Inflammation in PeriodontitisZIADE000736 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI MOUTSOPOULOS, NIKI · 2010 to 2025
$14.1M
6 · The paper itself

Abstract

Commensal microbiomes exert critical functions at barrier sites. In particular, establishment of the commensal microbiome after birth dictates immune functionality and tissue homeostasis at mucosal surfaces. To investigate the establishment and stability of the oral mucosal microbiome in mice, we evaluated oral microbiome communities shortly after birth, through adulthood, and up to 1 y of life in a controlled manner, using sequential oral samples from the same mice over time. We further evaluated transmissibility of oral microbiomes from parents and during cohousing experiments and evaluated susceptibility to oral inflammatory disease in mice harboring distinct microbiomes. Our work reveals basic principles in the establishment and stability of a health-associated oral microbiome after birth and provides insights that may be important for host-microbiome experimentation in animal models.

Indexed as

MicrobiotaAnimalsHomeostasisMiceMice, Inbred C57BLMouthSymbiosisgingival microbiomemicrobiome establishmentmicrobiome stabilitymicrobiome transferoral microbial acquisitionoral mucosal microbiome

Identifiers

PMID32345105
PMCPMC7243417

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.