ReviewJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020
Cerebral perfusion and blood-brain barrier assessment in brain trauma using contrast-enhanced near-infrared spectroscopy with indocyanine green: A review.
Review in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The trial behind it
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Who cites it
24 citing papers in PubMed, 37 citations in OpenAlex.
- Effect of Early Rehabilitation Nursing on Motor Function and Living Ability of Patients with Traumatic Brain Injury Based on Orem's Self-Care Theory.Computational intelligence and neuroscience · 2022Trial
- Physiological Responses to Prior Verbal Notice Before Passive Postural Change: A Randomized Crossover Exploratory Study of Circulatory and Autonomic Dynamics.Healthcare (Basel, Switzerland) · 2026Article
- 3D-PAULM: Integrated Photoacoustic Tomography and Ultrasound Localization Microscopy for Multiparametric Brain and Tumor Imaging.bioRxiv : the preprint server for biology · 2026Article
- Indocyanine green fluorescence-guided surgery in acute settings: state-of-the art.Frontiers in surgery · 2026Review
- Diffuse optical tomography system for acute traumatic brain injury in the intensive care unit: a prospective study on healthy volunteers.Journal of biomedical optics · 2025Article
- Multi-channel functional near-infrared spectroscopy for real-time monitoring during carotid artery stenting: a case series.Frontiers in neuroscience · 2025Article
- Enhancing daily living and cognitive functions in traumatic brain injury patients through Orem's self-care theory.Frontiers in neurology · 2024Article
- Use and Effectiveness of Electrosuit in Neurological Disorders: A Systematic Review with Clinical Implications.Bioengineering (Basel, Switzerland) · 2023Review
- Application of indocyanine green in surgery: A review of current evidence and implementation in trauma patients.World journal of gastrointestinal surgery · 2023Review
- Evaluation of MTT Heterogeneity of Perfusion CT Imaging in the Early Brain Injury Phase: An Insight into aSAH Pathopysiology.Brain sciences · 2023Article
- Fast Optical Signals for Real-Time Retinotopy and Brain Computer Interface.Bioengineering (Basel, Switzerland) · 2023Article
- Application of preoperative three-dimensional reconstruction combined with fluorescence imaging in simultaneous bilateral single-port thoracoscopic anatomical pneumonectomy.American journal of translational research · 2023Article
- Psychophysiological Assessment of Children with Cerebral Palsy during Robotic-Assisted Gait Training through Infrared Imaging.International journal of environmental research and public health · 2022Article
- Identification of Functional Cortical Plasticity in Children with Cerebral Palsy Associated to Robotic-Assisted Gait Training: An fNIRS Study.Journal of clinical medicine · 2022Article
- Sterically Shielded Hydrophilic Analogs of Indocyanine Green.The Journal of organic chemistry · 2022Article
- Near-infrared fluorescence imaging with indocyanine green for assessment of donor livers in a rat model of ischemia-reperfusion.BMC gastroenterology · 2022Article
- Indocyanine Green-Camptothecin Co-Loaded Perfluorocarbon Double-Layer Nanocomposite: A Versatile Nanotheranostics for Photochemotherapy and FDOT Diagnosis of Breast Cancer.Pharmaceutics · 2021Article
- A novel wireless optical technique for quantitative evaluation of cerebral perfusion pressure in a fluid percussion animal model of traumatic brain injury.Quantitative imaging in medicine and surgery · 2021Article
- Mismatch between Tissue Partial Oxygen Pressure and Near-Infrared Spectroscopy Neuromonitoring of Tissue Respiration in Acute Brain Trauma: The Rationale for Implementing a Multimodal Monitoring Strategy.International journal of molecular sciences · 2021Review
- The AMPAR antagonist perampanel protects the neurovascular unit against traumatic injury via regulating Sirt3.CNS neuroscience & therapeutics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
Abstract
Contrast-enhanced near-infrared spectroscopy (NIRS) with indocyanine green (ICG) can be a valid non-invasive, continuous, bedside neuromonitoring tool. However, its usage in moderate and severe traumatic brain injury (TBI) patients can be unprecise due to their clinical status. This review is targeted at researchers and clinicians involved in the development and application of contrast-enhanced NIRS for the care of TBI patients and can be used to design future studies. This review describes the methods developed to monitor the brain perfusion and the blood-brain barrier integrity using the changes of diffuse reflectance during the ICG passage and the results on studies in animals and humans. The limitations in accuracy of these methods when applied on TBI patients and the proposed solutions to overcome them are discussed. Finally, the analysis of relative parameters is proposed as a valid alternative over absolute values to address some current clinical needs in brain trauma care. In conclusion, care should be taken in the translation of the optical signal into absolute physiological parameters of TBI patients, as their clinical status must be taken into consideration. Discussion on where and how future studies should be directed to effectively incorporate contrast-enhanced NIRS into brain trauma care is given.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.