ArticleInnate immunity2020
CD40 up-regulation on dendritic cells correlates with Th17/Treg imbalance in chronic periodontitis in young population.
Article in Innate immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- The Role of Regulatory T Cells in Periodontitis With or Without Systemic Diseases: A Systematic Review.International journal of molecular sciences · 2026Pooled it
- In or out of control: Modulating regulatory T cell homeostasis and function with immune checkpoint pathways.Frontiers in immunology · 2022Pooled it
- Elevated interleukin-33, CD1c+ dendritic cells, and interleukin-17A in peritoneal fluid of patients with endometriosis: a case-control study.Molecular biology reports · 2026Article
- Advances in the biological functions of miR‑205 in various diseases (Review).Molecular medicine reports · 2026Review
- New insights into nanotherapeutics for periodontitis: a triple concerto of antimicrobial activity, immunomodulation and periodontium regeneration.Journal of nanobiotechnology · 2024Review
- Application of Nanomaterials Targeting Immune Cells in the Treatment of Chronic Inflammation.International journal of nanomedicine · 2024Review
- Lipidation of pneumococcal proteins enables activation of human antigen-presenting cells and initiation of an adaptive immune response.Frontiers in immunology · 2024Article
- The Murine Oral Metatranscriptome Reveals Microbial and Host Signatures of Periodontal Disease.Journal of dental research · 2023Article
- Comprehensive analysis of immune-related genes associated with the microenvironment of patients with unexplained infertility.Annals of translational medicine · 2023Article
- Exosomal miR-205-5p derived from periodontal ligament stem cells attenuates the inflammation of chronic periodontitis via targeting XBP1.Immunity, inflammation and disease · 2023Article
- Innovative biomaterials for the treatment of periodontal disease.Frontiers in dental medicine · 2023Review
- Local induction of regulatory T cells prevents inflammatory bone loss in ligature-induced experimental periodontitis in mice.Scientific reports · 2022Article
- mTOR Signaling in the Regulation of CD4+ T Cell Subsets in Periodontal Diseases.Frontiers in immunology · 2022Review
- Streptococcus pneumoniae Impairs Maturation of Human Dendritic Cells and Consequent Activation of CD4+ T Cells via Pneumolysin.Journal of innate immunity · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to discover the influence of age on the development of chronic periodontitis and illustrate the molecular mechanism in this process. Blood samples were collected from 63 chronic periodontitis patients and 30 healthy controls. Th17 cell/Foxp3
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.