ArticleClinical and experimental otorhinolaryngology2020
Characteristics of Obstructive Sleep Apnea Patients With a Low Body Mass Index: Emphasis on the Obstruction Site Determined by Drug-Induced Sleep Endoscopy.
Article in Clinical and experimental otorhinolaryngology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07132307 (Reducing Obstructive Sleep Apnea After Hypoglossal Nerve Stimulation Through), which is not on this map. Cited by 8 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Reducing Obstructive Sleep Apnea After Hypoglossal Nerve Stimulation Through
Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- Effect of lateral versus supine positioning on hypoxaemia in sedated adults: multicentre randomised controlled trial.BMJ (Clinical research ed.) · 2025Trial
- Perioperative Airway Management in Treacher Collins Syndrome With Obstructive Sleep Apnea: A Case Report.The American journal of case reports · 2026Article
- Upper airway obstruction during sleep in infants with laryngomalacia is frequently sleep-position-dependent.Pediatric research · 2025Article
- Sleep parameter characteristics of patients with OSA who have retropalatal circumferential narrowing and the clinical significance of lateral pharyngeal wall collapse during sleep.Sleep & breathing = Schlaf & Atmung · 2023Article
- Sleep bruxism events: an epiphenomenon of severe obstructive sleep apnea?Clinical oral investigations · 2023Article
- Critical closing pressure of the pharyngeal airway during routine drug-induced sleep endoscopy: feasibility and protocol.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- The Site of Airway Collapse in Sleep Apnea, Its Associations with Disease Severity and Obesity, and Implications for Mechanical Interventions.American journal of respiratory and critical care medicine · 2021Article
- Prediction of Epiglottic Collapse in Obstructive Sleep Apnea Patients: Epiglottic Length.Nature and science of sleep · 2021Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aimed to elucidate the patterns of upper airway collapse in obstructive sleep apnea (OSA) patients with a low body mass index (BMI).
methodsWe designed and conducted a retrospective cohort study. Consecutive patients diagnosed with OSA who underwent drug-induced sleep endoscopy (DISE) were included. Patients were classified into four groups according to their BMI. Age, sex, and polysomnography data were investigated. The patterns of upper airway collapse were characterized by the structures involved (soft palate, tongue base, lateral pharyngeal wall, and epiglottis). We compared the patterns of upper airway collapse in the supine and lateral decubitus position among the four BMI groups using the chi-square test and multivariate binary logistic regression analysis.
resultsA total of 627 patients (male, 517; mean age, 47.6±12.8 years) were included, consisting of 45, 79, 151, and 352 patients who were underweight or lower normal-weight (defined as the low BMI group), upper normal-weight, overweight, and obese, respectively. Severity indicators of OSA, such as the overall apnea-hypopnea index and duration of SaO2 below 90%, were significantly lower in patients with a low BMI than in obese patients, while their average oxygen saturation was significantly higher. The most common obstruction site in the supine position was the tongue base in patients with a low BMI (100%), whereas this obstruction site was significantly less common in obese patients (54.8%). Tongue base obstruction was mostly relieved in the lateral position, with no discernible obstruction in 86.7% of the low BMI patients.
conclusionAirway obstruction in OSA patients with a low BMI is mostly due to tongue base obstruction, which improves in the lateral position. These characteristics should be kept in mind when considering treatment options for this subgroup of OSA patients.
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