Evidence map›Paper›PMID 32344916›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

Multitarget Activities of Kleeb Bua Daeng, a Thai Traditional Herbal Formula, Against Alzheimer's Disease.

Chantha Chheng, Pornthip Waiwut, Kusawadee Plekratoke, Yaowared Chulikhit, Supawadee Daodee, Orawan Monthakantirat, Supaporn Pitiporn, Natdanai Musigavong, Pakakrong Kwankhao, Chantana Boonyarat

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  11. The Effect of Ethanol Extract fromCurrent issues in molecular biology · 2023
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  12. Multifunctionality ofCurrent issues in molecular biology · 2022
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  15. Effects ofResearch in pharmaceutical sciences · 2021
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  16. Multi-Target Actions of Acridones fromPharmaceuticals (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Chantha ChhengFaculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Pornthip WaiwutFaculty of Pharmaceutical Sciences, Ubon Ratchathani University, Ubon Ratchathani 34190, Thailand.
Kusawadee PlekratokeFaculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Yaowared ChulikhitFaculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Supawadee DaodeeFaculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Orawan MonthakantiratFaculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Supaporn PitipornChao Phya Abhaibhubejhr Hospital, Prachin Buri 25000, Thailand.
Natdanai MusigavongChao Phya Abhaibhubejhr Hospital, Prachin Buri 25000, Thailand.
Pakakrong KwankhaoChao Phya Abhaibhubejhr Hospital, Prachin Buri 25000, Thailand.ORCID 0000-0001-6829-4349
Chantana BoonyaratFaculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0003-4065-6090
Khon Kaen University · THChiangRai Prachanukroh Hospital · THUbon Ratchathani University · TH

Funding

Faculty of Pharmaceutical Sciences, Khon Kaen University -Khon Kaen University I62-00-21-02Khon Kaen University I62-00-21-03Thailand Center of Excellence for Life Sciences -Thailand Research Fund BDG6080006The Royal Scholarship under Her Royal Highness Princess Maha Chakri Sirindhorn Education Project to the Kingdom of Cambodia -
6 · The paper itself

Abstract

The Kleeb Bua Daeng formula (KBD) is a Thai traditional medicine for brain health promotion. On the basis of the activities of its individual components, the KBD could have good potential for the treatment of Alzheimer's disease (AD). Herein, we investigated the KBD as an AD treatment. The ethanol extracts of KBD and its components, i.e.,

Indexed as

acetylcholinesterase inhibitionantioxidantbeta-amyloid aggregationCentella asiaticaNelumbo nuciferaneuroprotectionPiper nigrum

Identifiers

PMID32344916
PMCPMC7281753
OpenAlexW3017529907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.