Evidence map›Paper›PMID 32344914›Full record

ArticleCancers2020

Solving the Time- and Frequency-Multiplexed Problem of Constrained Radiofrequency Induced Hyperthermia.

Andre Kuehne, Eva Oberacker, Helmar Waiczies, Thoralf Niendorf

Abstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Computational Design of a Thermal Applicator for Brain Hyperthermia Controlled by Capacitor Positioning in Loop Coils.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
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  12. Radiofrequency applicator concepts for thermal magnetic resonance of brain tumors at 297 MHz (7.0 Tesla).International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andre KuehneMRI.TOOLS GmbH, Robert-Roessle-Str. 10, 13125 Berlin, Germany.
Eva OberackerBerlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, 13125 Berlin, Germany.
Helmar WaicziesMRI.TOOLS GmbH, Robert-Roessle-Str. 10, 13125 Berlin, Germany.
Thoralf NiendorfMRI.TOOLS GmbH, Robert-Roessle-Str. 10, 13125 Berlin, Germany.

Funding

Bundesministerium für Bildung und Forschung FKZ: 01QE1815Eurostars MENTORA_4_EU, E! 12074Horizon 2020 Framework Programme MgSafe, grant agreement No 811226
6 · The paper itself

Abstract

Targeted radiofrequency (RF) heating induced hyperthermia has a wide range of applications, ranging from adjunct anti-cancer treatment to localized release of drugs. Focal RF heating is usually approached using time-consuming nonconvex optimization procedures or approximations, which significantly hampers its application. To address this limitation, this work presents an algorithm that recasts the problem as a semidefinite program and quickly solves it to global optimality, even for very large (human voxel) models. The target region and a desired RF power deposition pattern as well as constraints can be freely defined on a voxel level, and the optimum application RF frequencies and time-multiplexed RF excitations are automatically determined. 2D and 3D example applications conducted for test objects containing pure water (r

Indexed as

field focusingfield shapinghyperthermia treatment planningRF applicatorRF hyperthermiasemidefinite programmingthermal interventionthermal magnetic resonance

Identifiers

PMID32344914
PMCPMC7281622

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.