Evidence map›Paper›PMID 32344887›Full record

ArticleMicromachines2020

Passive Dielectrophoretic Focusing of Particles and Cells in Ratchet Microchannels.

Song-Yu Lu, Amirreza Malekanfard, Shayesteh Beladi-Behbahani, Wuzhou Zu, Akshay Kale, Tzuen-Rong Tzeng, Yao-Nan Wang, Xiangchun Xuan

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Electrokinetic nanoparticle transport in an interconnected porous environment: Decoupling cavity escape and directional bias.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Song-Yu LuDepartment of Mechanical Engineering, Clemson University, Clemson, SC 29634-0921, USA.
Amirreza MalekanfardDepartment of Mechanical Engineering, Clemson University, Clemson, SC 29634-0921, USA.
Shayesteh Beladi-BehbahaniDepartment of Biological Sciences, Clemson University, Clemson, SC 29634-0314, USA.
Wuzhou ZuDepartment of Mechanical Engineering, Clemson University, Clemson, SC 29634-0921, USA.
Akshay KaleElectrical Engineering Division, CAPE Building, Department of Engineering, University of Cambridge, 9 JJ Thomson Avenue, West Cambridge Site, Cambridge CB3 0FA, UK.
Tzuen-Rong TzengDepartment of Biological Sciences, Clemson University, Clemson, SC 29634-0314, USA.ORCID 0000-0003-1835-9639
Yao-Nan WangDepartment of Vehicle Engineering, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.
Xiangchun XuanDepartment of Mechanical Engineering, Clemson University, Clemson, SC 29634-0921, USA.ORCID 0000-0003-0158-4186
Clemson University · USNational Pingtung University of Science and Technology · TWUniversity of Cambridge · GB

Funding

National Science Foundation CBET- 1704379
6 · The paper itself

Abstract

Focusing particles into a tight stream is critical for many microfluidic particle-handling devices such as flow cytometers and particle sorters. This work presents a fundamental study of the passive focusing of polystyrene particles in ratchet microchannels via direct current dielectrophoresis (DC DEP). We demonstrate using both experiments and simulation that particles achieve better focusing in a symmetric ratchet microchannel than in an asymmetric one, regardless of the particle movement direction in the latter. The particle focusing ratio, which is defined as the microchannel width over the particle stream width, is found to increase with an increase in particle size or electric field in the symmetric ratchet microchannel. Moreover, it exhibits an almost linear correlation with the number of ratchets, which can be explained by a theoretical formula that is obtained from a scaling analysis. In addition, we have demonstrated a DC dielectrophoretic focusing of yeast cells in the symmetric ratchet microchannel with minimal impact on the cell viability.

Indexed as

dielectrophoresiselectrokineticmicrofluidicsparticle focusing

Identifiers

PMID32344887
PMCPMC7281238
OpenAlexW3020245050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.