Evidence map›Paper›PMID 32344679›Full record

ReviewJournal of clinical medicine2020

The COVID-19 Pandemic: A Comprehensive Review of Taxonomy, Genetics, Epidemiology, Diagnosis, Treatment, and Control.

Yosra A Helmy, Mohamed Fawzy, Ahmed Elaswad, Ahmed Sobieh, Scott P Kenney, Awad A Shehata

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04596839 (Antiviral Activity and Safety of Remdesivir in Bangladeshi Patients With Severe Coronavirus Disease), which is not on this map. Cited by 312 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
312citing papers in PubMed, 7 pooled it
16.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04596839 phase2completednot on this map

Antiviral Activity and Safety of Remdesivir in Bangladeshi Patients With Severe Coronavirus Disease (COVID-19): An Open Label, Multi-Center, Randomized Controlled Trial

TypeinterventionalSponsorDr. Md. Alimur RezaRan2020 to 2021Enrolled60ConditionsCovid19ArmsRemdesivir, Standard of Care
3 · Its place in the literature

Who cites it

312 citing papers in PubMed, 7 syntheses or guidelines pooled it, 724 citations in OpenAlex.

  1. Pooled it
  2. Impact of COVID-19 Vaccination onInternational journal of fertility & sterility · 2024
    Pooled it
  3. Pooled it
  4. Detecting SARS-CoV-2 in sludge samples: A systematic review.The Science of the total environment · 2023
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Review
  9. Article
  10. COVID-19, the disease that changed the world.Medicine and pharmacy reports · 2026
    Review
  11. Review
  12. Article
  13. Observational
  14. Inhibitory Effect ofTheScientificWorldJournal · 2026
    Article
  15. Review
  16. Article
  17. Article
  18. Antibiotic Alternatives and Next-Generation Therapeutics forAntibiotics (Basel, Switzerland) · 2025
    Review
  19. Article
  20. Review

252 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Yosra A HelmyDepartment of Veterinary Preventive Medicine, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH 44691, USA.ORCID 0000-0003-1470-5418
Mohamed FawzyDepartment of Virology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt.
Ahmed ElaswadDepartment of Animal Wealth Development, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt.
Ahmed SobiehDepartment of Radiology, University of Massachusetts Medical School, Worcester, MA 01655, USA.
Scott P KenneyDepartment of Veterinary Preventive Medicine, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH 44691, USA.ORCID 0000-0002-7449-2066
Awad A ShehataAvian and Rabbit Diseases Department, Faculty of Veterinary Medicine, Sadat City University, Sadat 32897, Egypt.
Suez Canal University · EGThe Ohio State University · USUniversity of Massachusetts Chan Medical School · USUniversity of Sadat City · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A pneumonia outbreak with unknown etiology was reported in Wuhan, Hubei province, China, in December 2019, associated with the Huanan Seafood Wholesale Market. The causative agent of the outbreak was identified by the WHO as the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), producing the disease named coronavirus disease-2019 (COVID-19). The virus is closely related (96.3%) to bat coronavirus RaTG13, based on phylogenetic analysis. Human-to-human transmission has been confirmed even from asymptomatic carriers. The virus has spread to at least 200 countries, and more than 1,700,000 confirmed cases and 111,600 deaths have been recorded, with massive global increases in the number of cases daily. Therefore, the WHO has declared COVID-19 a pandemic. The disease is characterized by fever, dry cough, and chest pain with pneumonia in severe cases. In the beginning, the world public health authorities tried to eradicate the disease in China through quarantine but are now transitioning to prevention strategies worldwide to delay its spread. To date, there are no available vaccines or specific therapeutic drugs to treat the virus. There are many knowledge gaps about the newly emerged SARS-CoV-2, leading to misinformation. Therefore, in this review, we provide recent information about the COVID-19 pandemic. This review also provides insights for the control of pathogenic infections in humans such as SARS-CoV-2 infection and future spillovers.

Indexed as

controlCOVID-19diagnosisepidemiologygeneticsOne Healthoutbreakpneumoniapublic healthSARS-CoV-2treatment

Identifiers

PMID32344679
PMCPMC7230578
OpenAlexW3020654962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.