ArticleKidney research and clinical practice2020
Reduced risk for chronic kidney disease after recovery from metabolic syndrome: A nationwide population-based study.
Article in Kidney research and clinical practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 38 citations in OpenAlex.
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- Changes in metabolic syndrome status and risk of chronic kidney disease over a decade of follow-up in the Iranian population.Scientific reports · 2025Article
- Mendelian Randomization Studies: Opening a New Window in the Study of Metabolic Diseases and Chronic Kidney Disease.Endocrine, metabolic & immune disorders drug targets · 2025Review
- The impact of metabolic component count on IgA nephropathy prognosis.Scientific reports · 2024Article
- Causal effect of lipoprotein(a) level on chronic kidney disease of European ancestry: a two-sample Mendelian randomization study.Renal failure · 2024Article
- Metabolic syndrome as a risk factor for the development of kidney dysfunction: a meta-analysis of observational cohort studies.Journal of diabetes and metabolic disorders · 2024Review
- Risk of mortality and cause of death according to kidney function parameters: a nationwide observational study in Korea.Kidney research and clinical practice · 2024Article
- New-onset metabolic syndrome is associated with accelerated renal function decline partially through elevated uric acid: an epidemiological cohort study.Frontiers in endocrinology · 2024Article
- Article
- Nutrition and quality of life in chronic kidney disease patients: a practical approach for salt restriction.Kidney research and clinical practice · 2022Article
- High Triglyceride-Glucose Index with Renal Hyperfiltration and Albuminuria in Young Adults: The Korea National Health and Nutrition Examination Survey (KNHANES V, VI, and VIII).Journal of clinical medicine · 2022Article
- Article
- Prevalence and associations of metabolic syndrome in patients with alcohol use disorder.Scientific reports · 2022Article
- Abdominal periaortic and renal sinus fat attenuation indices measured on computed tomography are associated with metabolic syndrome.European radiology · 2022Article
- Transiently Observed Trace Albuminuria on Urine Dipstick Test Is Associated With All-Cause Death, Cardiovascular Death, and Incident Chronic Kidney Disease: A National Health Insurance Service-National Sample Cohort in Korea.Frontiers in cardiovascular medicine · 2022Article
- Correlation of Body Mass Index with Clinicopathologic Parameters in Patients with Idiopathic Membranous Nephropathy.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Association of chronic kidney disease with all-cause mortality in patients hospitalized for atrial fibrillation and impact of clinical and socioeconomic factors on this association.Frontiers in cardiovascular medicine · 2022Article
- Causal effects of education on chronic kidney disease: a Mendelian randomization study.Clinical kidney journal · 2021Article
- How important is dietary management in chronic kidney disease progression? A role for low protein diets.The Korean journal of internal medicine · 2021Review
- Nonalcoholic Fatty Liver Disease and Chronic Kidney Disease: A Review of Links and Risks.Clinical and experimental gastroenterology · 2021Review
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMetabolic syndrome (MetS) is linked to various chronic comorbidities, including chronic kidney disease (CKD). However, few large studies have addressed whether recovery from MetS is associated with reduction in the risks of such comorbidities.
methodsThis nationwide population-based study in Korea screened 10,664,268 people who received national health screening ≥ 3 times between 2012 and 2016. Those with a history of major cardiovascular events or preexisting CKD were excluded. We classified study groups into four, according to the course of MetS state, as defined by the harmonizing criteria. The main study outcome was incidental CKD (estimated glomerular filtration rate < 60 mL/min/1.73 m
resultsFour study groups included 6,315,301 subjects: 4,537,869 people without MetS, 1,034,605 with chronic MetS, 438,287 who developed MetS, and 304,540 who recovered from preexisting MetS. Those who developed MetS demonstrated higher risk of CKD (adjusted odds ratio [OR], 1.26 [1.23-1.29]) than did those who did not develop MetS. In contrast, MetS-recovery was associated with decreased risk of CKD (adjusted OR, 0.84 [0.82-0.86]) than that in people with chronic MetS. Among the MetS components, change in hypertension was associated with the largest difference in CKD risk.
conclusionReducing or preventing MetS may reduce the burden of CKD on a population-scale. Clinicians should consider the clinical importance of altering MetS status for risk of CKD.
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