ArticlePhotodiagnosis and photodynamic therapy2020
Imaging of hypoxia, oxygen consumption and recovery in vivo during ALA-photodynamic therapy using delayed fluorescence of Protoporphyrin IX.
Article in Photodiagnosis and photodynamic therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Intracellular oxygen measurement in vivo by smartphone readout of endogenous Protoporphyrin IX delayed fluorescence.Biosensors & bioelectronics · 2026Article
- Imaging lymphatic function and inflammation response through hypoxia via endogenous biomarker.Journal of biomedical optics · 2026Article
- Emerging uses of 5-aminolevulinic-acid-induced protoporphyrin IX in medicine: a review of multifaceted, ubiquitous, molecular diagnostic, therapeutic, and theranostic opportunities.Journal of biomedical optics · 2025Review
- ALA-based photodynamic priming in murine skin increases blood flow and oxygenation.Journal of biomedical optics · 2025Article
- Enhanced porphyrin-based hypoxia imaging by temporal oversampling of delayed fluorescence signal.Journal of biomedical optics · 2025Article
- Application of liposomal nanoparticles of berberine in photodynamic therapy of A549 lung cancer spheroids.Biochemistry and biophysics reports · 2024Article
- Photodynamic Therapy Using a Rose-Bengal Photosensitizer for Hepatocellular Carcinoma Treatment: Proposition for a Novel Green LED-Based Device for In Vitro Investigation.Biomedicines · 2024Article
- Cyanine dyes in the mitochondria-targeting photodynamic and photothermal therapy.Communications chemistry · 2024Review
- All organic nanomedicine for PDT-PTT combination therapy of cancer cells in hypoxia.Scientific reports · 2024Article
- Review of optical reporters of radiation effectsJournal of biomedical optics · 2023Review
- Protoporphyrin IX delayed fluorescence imaging: a modality for hypoxia-based surgical guidance.Journal of biomedical optics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundHypoxic lesions often respond poorly to cancer therapies. Particularly, photodynamic therapy (PDT) consumes oxygen in treated tissues, which in turn lowers its efficacy. Tools for online monitoring of intracellular pO
methodsThe pO
resultspO
conclusionsTime-gated imaging of PpIX DF seems to be a unique tool for direct online monitoring of pO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.