Evidence map›Paper›PMID 32344147›Full record

ArticleThe ocular surface2020

Role of optical coherence tomography angiography in the characterization of vascular network patterns of ocular surface squamous neoplasia.

Zhiping Liu, Carol L Karp, Anat Galor, Ghada J Al Bayyat, Hong Jiang, Jianhua Wang

Open access · greenAbstract read
In one paragraph

Article in The ocular surface, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
  2. Review
  3. Optical coherence tomography angiography in evaluating the response of ocular surface squamous neoplasia to topical immunotherapy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  4. Enhanced Imaging of Ocular Surface Lesions.Journal of clinical medicine · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Current clinical applications of anterior segment optical coherence tomography angiography: a review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Review
  9. Article
  10. Article
  11. Role of AS-OCT in Managing Corneal Disorders.Diagnostics (Basel, Switzerland) · 2022
    Review
  12. Review
  13. Article
  14. The role of imaging technologies for ocular surface tumors.Current opinion in ophthalmology · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Zhiping LiuOphthalmic Center, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, USA.
Carol L KarpDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, USA.
Anat GalorDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, USA; Department of Ophthalmology, Miami Veterans Administration Medical Center, Miami, USA.
Ghada J Al BayyatDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, USA.
Hong JiangDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, USA; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.
Jianhua WangDepartment of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, USA. Electronic address: jwang3@med.miami.edu.
University of Miami · USGuangzhou Medical University · CNUnited States Department of Veterans Affairs · US

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Dmitry V Ivanov · 2004 to 2026
$12.2M
Dry Eye and MicroenvironmentR01EY026174 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GALOR, ANAT, KUMAR, NARESH · 2016 to 2020
$1.9M
NEI NIH HHS P30 EY014801NEI NIH HHS R01 EY026174
6 · The paper itself

Abstract

purposeTo visualize and quantify vascular networks in individuals with ocular surface squamous neoplasia (OSSN) through optical coherence tomography angiography (OCTA).

methodCross-sectional study of OSSN patients. Vascular networks were measured by OCTA in the epithelium and sub-epithelial space in the tumors, adjacent tissue, and in the contralateral eye. Vessel area density (VAD, percent of blood vessels within 2.14 mm

resultsFifteen patients with OSSN were included. The mean age was 61 ± 12 years and the majority were male (80%). The mean tumor area, volume, depth, and TTD were 28.0 ± 9.0 mm

conclusionsOCTA imaging allowed for visualization and quantification of vessel structure and density within, under, and surrounding OSSN.

Indexed as

Carcinoma, Squamous CellEye NeoplasmsAgedAngiographyCross-Sectional StudiesHumansMaleMiddle AgedTomography, Optical CoherenceOCTAOcular surface squamous neoplasiaOptical coherence tomography angiographyVascular networksVessel area density

Identifiers

PMID32344147
PMCPMC9449867
OpenAlexW3020647381

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.