Evidence map›Paper›PMID 32344119›Full record

ReviewBiomedical journal2021

Intravascular Large B-cell lymphoma: A case series and review of literatures.

Yuen-Chin Ong, Hsiao-Wen Kao, Wen-Yu Chuang, Yu-Shin Hung, Tung-Liang Lin, Hung Chang, Ming-Chung Kuo

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Biomedical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. What to know about rare B-cell malignancies in 2025.Hematology. American Society of Hematology. Education Program · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Intravascular Large B Cell Lymphoma - Still a Diagnostic Dilemma.Journal of community hospital internal medicine perspectives · 2022
    Article
  15. Article
  16. Article
  17. Intravascular large B-cell lymphoma affecting multiple cranial nerves: A histopathological study.Neuropathology : official journal of the Japanese Society of Neuropathology · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yuen-Chin OngDivision of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Hsiao-Wen KaoDivision of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Wen-Yu ChuangCollege of Medicine, Chang Gung University, Taoyuan, Taiwan; Division of Pathology, Chang Gung Memorial Hospital at Taipei, Taipei, Taiwan.
Yu-Shin HungDivision of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Tung-Liang LinDivision of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Hung ChangDivision of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; Center of Hemophilia and Coagulation Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Ming-Chung KuoDivision of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan. Electronic address: k12069@cgmh.org.tw.
Chang Gung University · TWLinkou Chang Gung Memorial Hospital · TWChang Gung Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntravascular large B-cell lymphoma (IVLBCL) is a rare subtype of non-Hodgkin lymphoma with uncommon clinical presentations and poor prognosis. The purpose of this study is to report the clinical features and outcome of IVLBCL in a single institution of Taiwan.

methodsTen patients with IVLBCL diagnosed from June 2006 to January 2018 were retrospectively reviewed.

resultsThe median age was 61 (range 39-88) years. The most common presentation was fever (90%), cytopenia (90%), and confusion (50%). For all patients, the median progression free survival (PFS) and overall survival (OS) were 12.6 (95% confidence interval [CI] 0.0-76.1) and 18.8 (95% CI 0-59.3) months, respectively. Six patients received rituximab combined chemotherapy, and the other one patient was treated with chemotherapy alone. Six of seven (85.7%) patients achieved complete response after chemotherapy. The median PFS and OS for six patients who completed treatment were not reached. Three-year PFS and OS rates were 80% and 75%, respectively.

conclusionOur study showed that patients might achieve durable remission after rituximab-based chemotherapy. The outcome of IVLBCL patients may further improve if early diagnosis and prompt treatment were made.

Indexed as

Lymphoma, Large B-Cell, DiffuseAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsHumansMiddle AgedRetrospective StudiesRituximabSurvival RateRituximabHemophagocytosisIntravascular large B-Cell lymphomaRituximab

Identifiers

PMID32344119
PMCPMC8514799
OpenAlexW3017555863

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.