Evidence map›Paper›PMID 32343708›Full record

SynthesisPloS one2020

Reinforced education improves the quality of bowel preparation for colonoscopy: An updated meta-analysis of randomized controlled trials.

Xiaoyang Guo, Xin Li, Zhiyan Wang, Junli Zhai, Qiang Liu, Kang Ding, Yanglin Pan

Abstract readMeta-Analysis
In one paragraph

Synthesis in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. A Systematic Review on the Effective Teaching Strategies and Methods for Cancer Patient Education.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Measuring and Improving Quality of Colonoscopy for Colorectal Cancer Screening.Techniques and innovations in gastrointestinal endoscopy · 2022
    Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoyang GuoDepartment of Ultrasound, The 305 Hospital of PLA, Bejing, China.
Xin LiDepartment of Pneumology, The Second Medical Center of PLA General Hospital, Beijing, China.
Zhiyan WangDepartment of Pneumology, The Second Medical Center of PLA General Hospital, Beijing, China.
Junli ZhaiDepartment of Pneumology, The Second Medical Center of PLA General Hospital, Beijing, China.
Qiang LiuDepartment of Ultrasound, The 305 Hospital of PLA, Bejing, China.
Kang DingDepartment of Ultrasound, The 305 Hospital of PLA, Bejing, China.
Yanglin PanXijing Hospital of Digestive Diseases, Air Force Medical University, Xi'an, China.ORCID 0000-0002-4596-4642

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsInadequate bowel preparation (BP) is an unfavorable factor that influence the success of colonoscopy. Although standard education (SE) given to patients are proved useful to avoid inadequate BP. Studies concerning the effects of reinforced education (RE) on the quality of BP were inconsistent. The aim of this updated meta-analysis of randomized controlled trial was to compare the quality of BP between patients receiving RE in addition to SE and those receiving SE alone.

methodsMEDLINE, EMBASE, Web of Science and the Cochrane Library were systemically searched to identify the relevant studies published through April 2019. The primary outcome was the rate of adequate BP. Subgroup analyses were conducted. Secondary outcomes included BP score, adenoma detection rate (ADR), polyp detection rate (PDR), insertion time, withdrawal time, adverse events, >80% purgative intake and diet compliance. Dichotomous variables were reported as odds ratio (OR) with 95% confidence interval (CI). Continuous data were reported as mean difference (MD) with 95%CI. Pooled estimates of OR or MD were calculated using a random-effects model. Statistical heterogeneity was accessed by calculating the I2 value. A P value less than 0.05 was considered significant.

resultsA total of 18 randomized controlled trails (N = 6536) were included in this meta-analysis. Patients who received RE had a better BP quality than those only receiving SE (OR 2.59, 95%CI: 2.09-3.19; P<0.001). A higher ADR (OR 1.35; 95%CI: 1.06-1.72; P = 0.020) and PDR (OR 1.24, 95%CI: 1.02-1.50; P = 0.030), shorter insertion (MD -0.76; 95%CI: -1.48-(-0.04); P = 0.040) and withdrawal time (MD -0.83; 95%CI: -1.83-(-0.28); P = 0.003), less nausea/vomiting (OR 0.78; 95%CI: 0.64-0.97; P = 0.020) and abdominal distension (OR 0.72; 95%CI: 0.68-0.92; P = 0.020) were achieved in the RE group. More patients had >80% purgative intake (OR 2.17; 95%CI, 1.09-4.32; P = 0.030) and were compliant with diet restriction (OR 2.38; 95%CI: 1.79-3.17; P<0.001) in the RE group.

conclusionRE significantly improved BP quality, increased ADR and PDR, decreased insertion and withdrawal time and adverse events.

Indexed as

ColonoscopyPatient Education as TopicAdenomaHumansLaxativesNauseaOdds RatioPolyethylene GlycolsPolypsRandomized Controlled Trials as TopicLaxativesPolyethylene Glycols

Identifiers

PMID32343708
PMCPMC7188205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.