Evidence map›Paper›PMID 32343370›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2021

Prevalence and predictive value of ICD-11 post-traumatic stress disorder and Complex PTSD diagnoses in children and adolescents exposed to a single-event trauma.

Rachel Elliott, Anna McKinnon, Clare Dixon, Adrian Boyle, Fionnuala Murphy, Theresa Dahm, Emma Travers-Hill, Cari-Lène Mul, Sarah-Jane Archibald, Patrick Smith and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 50 citations in OpenAlex.

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  19. Frontiers in pharmacology · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Rachel ElliottMRC: Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Anna McKinnonMRC: Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Clare DixonMRC: Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Adrian BoyleCambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Fionnuala MurphyMRC: Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Theresa DahmMRC: Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Emma Travers-HillMRC: Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Cari-Lène MulDepartment of Psychology, Anglia Ruskin University, Cambridge, UK.
Sarah-Jane ArchibaldCambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Patrick SmithInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Tim DalgleishMRC: Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Richard Meiser-StedmanMRC: Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.ORCID 0000-0002-0262-623X
Caitlin HitchcockMRC: Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.ORCID 0000-0002-2435-0713
MRC Cognition and Brain Sciences Unit · GBCambridge University Hospitals NHS Foundation Trust · GBAnglia Ruskin University · GBKing's College London · GBUniversity of East Anglia · GB

Funding

Department of HealthMedical Research Council MC_EX_G0802821Medical Research Council MC_U105559837Medical Research Council MC_U105579215Medical Research Council MC_UU_00005/10Medical Research Council SUAG/043 G101400Medical Research Council (MRC) Clinician Scientist Fellowship G0802821Wellcome TrustWellcome Trust 104908/Z/14/ZWellcome Trust 107496/Z/15/Z
6 · The paper itself

Abstract

backgroundThe 11th edition of the International Classification of Diseases (ICD-11) made a number of significant changes to the diagnostic criteria for post-traumatic stress disorder (PTSD). We sought to determine the prevalence and 3-month predictive values of the new ICD-11 PTSD criteria relative to ICD-10 PTSD, in children and adolescents following a single traumatic event. ICD-11 also introduced a diagnosis of Complex PTSD (CPTSD), proposed to typically result from prolonged, chronic exposure to traumatic experiences, although the CPTSD diagnostic criteria do not require a repeated experience of trauma. We therefore explored whether children and adolescents demonstrate ICD-11 CPTSD features following exposure to a single-incident trauma.

methodData were analysed from a prospective cohort study of youth aged 8-17 years who had attended an emergency department following a single trauma. Assessments of PTSD, CPTSD, depressive and anxiety symptoms were performed at two to four weeks (n = 226) and nine weeks (n = 208) post-trauma, allowing us to calculate and compare the prevalence and predictive value of ICD-10 and ICD-11 PTSD criteria, along with CPTSD. Predictive abilities of different diagnostic thresholds were undertaken using positive/negative predictive values, sensitivity/specificity statistics and logistic regressions.

resultsAt Week 9, 15 participants (7%) were identified as experiencing ICD-11 PTSD, compared to 23 (11%) experiencing ICD-10 PTSD. There was no significant difference in comorbidity rates between ICD-10 and ICD-11 PTSD diagnoses. Ninety per cent of participants with ICD-11 PTSD also met criteria for at least one CPTSD feature. Five participants met full CPTSD criteria.

conclusionsReduced prevalence of PTSD associated with the use of ICD-11 criteria is likely to reduce identification of PTSD relative to using ICD-10 criteria but not relative to DSM-4 and DSM-5 criteria. Diagnosis of CPTSD is likely to be infrequent following single-incident trauma.

Indexed as

International Classification of DiseasesStress Disorders, Post-TraumaticAdolescentChildDiagnostic and Statistical Manual of Mental DisordersHumansPrevalenceProspective StudiesadolescentchildComplex PTSDInternational Classification of DiseasesPost-traumatic stress disordertrauma

Identifiers

PMID32343370
PMCPMC7984249
OpenAlexW3020727739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.