Evidence map›Paper›PMID 32343231›Full record

SynthesisThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2020

Does periampullary diverticulum affect ERCP cannulation and post-procedure complications? an up-to-date meta-analysis.

Peilei Mu, Ping Yue, Fangwei Li, Yanyan Lin, Ying Liu, Wenbo Meng, Wence Zhou, Xun Li

Open access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  7. Observational
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  13. Periampullary diverticulum in endoscopic retrograde cholangiopancreatography: A paper tiger?Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Peilei MuThe First Clinical Medical School of Lanzhou University, Lanzhou, Gansu, China; Department of Special Minimally Invasive Surgery, The First Hospital of Lanzhou University, Lanzhou, Gansu, China;Peilei Mu and Ping Yue contributed equally to this work.
Ping YueThe First Clinical Medical School of Lanzhou University, Lanzhou, Gansu, China; Department of Special Minimally Invasive Surgery, The First Hospital of Lanzhou University, Lanzhou, Gansu, China;Peilei Mu and Ping Yue contributed equally to this work.
Fangwei LiDepartment of Social Medicine and Health Management, College of Public Health, Zhengzhou University, Zhengzhou, Henan, China.
Yanyan LinDepartment of Special Minimally Invasive Surgery, The First Hospital of Lanzhou University, NO.1 DongGang West Road, LanZhou, China;Hepatopancreatobiliary Surgery Institute of Gansu Province, Clinical Medical College Cancer Center of Lanzhou University, NO.1 DongGang West Road, LanZhou, China.
Ying LiuDepartment of Foreign Languages, Lanzhou University, Lanzhou, China.
Wenbo MengThe First Clinical Medical School of Lanzhou University, Lanzhou, Gansu, China;Department of Special Minimally Invasive Surgery, The First Hospital of Lanzhou University, Lanzhou, Gansu, China;Gansu Province Key Laboratory Biotherapy and Regenerative Medicine, Lanzhou, Gansu, China.
Wence ZhouThe First Clinical Medical School of Lanzhou University, Lanzhou, Gansu, China;The Second Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou, Gansu, China.
Xun LiThe First Clinical Medical School of Lanzhou University, Lanzhou, Gansu, China;The Fifth Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou, Gansu, China.
First Hospital of Lanzhou University · CNLanzhou University of Technology · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research conclusions differ on the impact of periampullary diverticulum (PAD) on endoscopic retrograde cholangiopancreatography (ERCP). An up-to-date meta-analysis evaluated the role of PAD in ERCP, especially in terms of cannulation failure and early complications. A comprehensive literature search was performed. All statistical analyses were carried out with the Review Manager 5.3 software. Horizontal lines represented a 95% confidence interval (CI) and the area of each square in forest plots. Twenty-six studies including 23 826 patients with or without PAD who underwent ERCP were evaluated. PAD was associated with an increase in the overall cannulation failure rate (RR=1.46, 95% CI: 1.27-1.67; p<.00001), but in the subgroup of studies performed post-2000, PAD was irrelevant to cannulation failure (RR=1.16, 95% CI: 0.96-1.41; p=0.12). In overall analyses, PAD was also associated with a high risk of ERCP-related pancreatitis (RR=1.32, 95% CI: 1.10-1.59; p=0.003), perforation (RR=1.73, 95% CI: 1.06-2.82; p=0.030), and bleeding (RR=1.48, 95% CI: 1.13-1.93; p=0.005). The presence of PAD increased the overall cannulation failure rate, but not the rate post-2000. PAD also affected the occurrence of early pancreatitis, perforation, and bleeding.

Indexed as

AdultAgedAged, 80 and overAmpulla of VaterCatheterizationCholangiopancreatography, Endoscopic RetrogradeCommon Bile Duct DiseasesDiverticulumFemaleHumansMaleMiddle AgedPostoperative ComplicationsTreatment Outcome

Identifiers

PMID32343231
PMCPMC7197928
OpenAlexW3024713844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.