Evidence map›Paper›PMID 32343228›Full record

ArticleeLife2020

Divergent Cl

Lilia Leisle, Yanyan Xu, Eva Fortea, Sangyun Lee, Jason D Galpin, Malvin Vien, Christopher A Ahern, Alessio Accardi, Simon Bernèche

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Structural basis of pH-dependent activation in a CLC transporter.Nature structural & molecular biology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Q-cubed mutant cues clues to CLC antiport mechanism.The Journal of general physiology · 2021
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Lilia Leisle *Department of Anesthesiology, Weill Cornell Medical College, New York, United States.ORCID 0000-0003-3987-4269
Yanyan Xu *SIB Swiss Institute of Bioinformatics, University of Basel, Basel, Switzerland.
Eva ForteaDepartment of Physiology and Biophysics, Weill Cornell Medical College, New York, United States.ORCID 0000-0003-4328-8940
Sangyun LeeDepartment of Anesthesiology, Weill Cornell Medical College, New York, United States.
Jason D GalpinDepartment of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, United States.
Malvin VienDepartment of Anesthesiology, Weill Cornell Medical College, New York, United States.
Christopher A AhernDepartment of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, United States.ORCID 0000-0002-7975-2744
Alessio AccardiDepartment of Anesthesiology, Weill Cornell Medical College, New York, United States.ORCID 0000-0002-6584-0102
Simon BernècheSIB Swiss Institute of Bioinformatics, University of Basel, Basel, Switzerland.ORCID 0000-0002-6274-4094
Cornell University · USSIB Swiss Institute of Bioinformatics · CHUniversity of Iowa · US

Funding

Chemical Biology of Voltage-Gated Sodium and Potassium ChannelsR01GM106569 · NIGMS · UNIVERSITY OF IOWA · PI AHERN, CHRISTOPHER A · 2013 to 2022
$2.7M
Atomic basis for chloride channel and transporter gating and selectivityR01GM128420 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI ACCARDI, ALESSIO · 2019 to 2022
$1.5M
The Facility for Atomic MutagenesisR24NS104617 · NINDS · UNIVERSITY OF IOWA · PI AHERN, CHRISTOPHER A · 2018 to 2021
$1.0M
NIGMS NIH HHS R01 GM106569NIGMS NIH HHS R01 GM128420NINDS NIH HHS R24 NS104617Swiss National Science Foundation PP00P3_139205
6 · The paper itself

Abstract

The CLC family comprises H

Indexed as

AntiportersChloride ChannelsChloridesEscherichia coli ProteinsIon Channel GatingIon TransportMolecular Dynamics SimulationProtonsAntiportersChloride ChannelsChloridesCLC-ec1 protein, E coliEscherichia coli ProteinsProtonsactive transportbiochemistrychemical biologyion channelsmembrane proteinmolecular biophysicsstructural biologyxenopus

Identifiers

PMID32343228
PMCPMC7274781
OpenAlexW3020136339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.