ArticleAge and ageing2020
Transitions between frailty states in the very old: the influence of socioeconomic status and multi-morbidity in the Newcastle 85+ cohort study.
Article in Age and ageing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between oral frailty and physical frailty among older adults: a meta-analysis.BMC oral health · 2026Pooled it
- Trial
- Disability transitions and life expectancy: a national longitudinal study on social isolation and loneliness in China.Global health action · 2026Article
- Digital exclusion, functional limitations transitions, and life expectancy: a multinational longitudinal study.SSM - population health · 2026Article
- Factors associated with sustained robustness in older adults: an 8-year multinational longitudinal study using SHARE data.BMC geriatrics · 2026Observational
- Frailty and major late-life transitions in very old adults: contrasting biomarker patterns of GDF-15 and NT-proBNP in the Kawasaki Aging and Wellbeing Project.GeroScience · 2026Article
- oral functional limitation and long-term frailty trajectories: a 6-year cohort study of community-dwelling older adults in Korea.GeroScience · 2026Article
- Patterns of Vulnerability: Frailty, Multimorbidity, and Physical Health-Related Quality of Life in Institutionalised Older Adults.Healthcare (Basel, Switzerland) · 2026Article
- Hobby engagement, disability transitions, and life expectancy: a multinational longitudinal study.Journal of global health · 2026Article
- Six-year transition patterns of activities of daily living in octogenarians: Tokyo oldest old in total health study.BMC geriatrics · 2025Article
- Association of multimorbidity patterns and order of physical frailty and cognitive impairment occurrence: a prospective cohort study.Age and ageing · 2025Article
- Associated factors of frailty among community-dwelling older adults with multimorbidity from a health ecological perspective: a cross-sectional study.BMC geriatrics · 2025Article
- Understanding hospital activity and outcomes for people with multimorbidity using electronic health records.Scientific reports · 2025Article
- The association between multimorbidity patterns and physical frailty among middle-aged and older community-dwelling adults: the mediating role of depressive symptoms.Frontiers in public health · 2025Article
- Association between changes of frailty status/frailty components status and rapid loss of kidney function in middle- aged and older populations.BMC nephrology · 2024Article
- Association of chronic conditions and physical multimorbidity with new-onset incontinence in a nationwide prospective cohort study of older adults ≥ 50 years in China.Age and ageing · 2024Article
- U-shaped association between sleep duration and frailty in Chinese older adults: a cross-sectional study.Frontiers in public health · 2024Article
- Change in a Claims-Based Frailty Index, Mortality, and Health Care Costs in Medicare Beneficiaries.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Exercise to Prevent and Manage Frailty and Fragility Fractures.Current osteoporosis reports · 2023Review
- Associations between multimorbidity and frailty transitions among older Americans.Journal of cachexia, sarcopenia and muscle · 2023Article
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7 authors.
Funding
Abstract
backgroundUsing Newcastle 85+ Study data, we investigated transitions between frailty states from age 85 to 90 years and whether multi-morbidities and socioeconomic status (SES) modify transitions.
methodsThe Newcastle 85+ Study is a prospective, longitudinal cohort study of all people born in 1921 in Newcastle and North Tyneside. Data included: a multidimensional health assessment; general practice record review (GPRR) and date of death. Using the Fried phenotype (participants defined as robust, pre-frail or frail), frailty was measured at baseline, 18, 36 and 60 months.
resultsFrailty scores were available for 82% (696/845) of participants at baseline. The prevalence of frailty was higher in women (29.7%, 123/414) than men (17.7%, 50/282) at baseline and all subsequent time points. Of those robust at baseline, 44.6% (50/112) remained robust at 18 months and 28% (14/50) at age 90. Most (52%) remained in the same state across consecutive interviews; only 6% of the transitions were recovery (from pre-frail to robust or frail to pre-frail), and none were from frail to robust. Four or more diseases inferred a greater likelihood of progression from robust to pre-frail even after adjustment for SES. SES did not influence the likelihood of moving from one frailty state to another.
conclusionsAlmost half the time between age 85 and 90, on average, was spent in a pre-frail state; multi-morbidity increased the chance of progression from robust and to frail; greater clinical intervention at the onset of a first chronic illness, to prevent transition to multi-morbidity, should be encouraged.
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