Evidence map›Paper›PMID 32342858›Full record

ArticleeLife2020

Disparate expression specificities coded by a shared Hox-C enhancer.

Steve W Miller, James W Posakony

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Hox genes in development and beyond.Development (Cambridge, England) · 2023
    Article
  3. Transcriptional enhancers and their communication with gene promoters.Cellular and molecular life sciences : CMLS · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Steve W MillerDivision of Biological Sciences, Section of Cell & Developmental Biology, University of California San Diego, La Jolla, United States.ORCID 0000-0001-7610-6336
James W PosakonyDivision of Biological Sciences, Section of Cell & Developmental Biology, University of California San Diego, La Jolla, United States.ORCID 0000-0001-6377-1732
University of California San Diego · US

Funding

Functional Architecture of Developmental Cis-Regulatory ModulesR01GM120377 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI POSAKONY, JAMES W. · 2017 to 2020
$1.2M
NIGMS NIH HHS R01 GM120377NIH HHS 1R01GM120377
6 · The paper itself

Abstract

Can a single regulatory sequence be shared by two genes undergoing functional divergence? Here we describe a single promiscuous enhancer within the

Indexed as

AnimalsDrosophilaDrosophila ProteinsEnhancer Elements, GeneticEvolution, MolecularGene Expression RegulationHomeodomain ProteinsInsect ProteinsRepressor ProteinsRNA, MessengerTranscription FactorsDrosophila ProteinsHomeodomain ProteinsHox3 protein, insectInsect Proteinspb protein, DrosophilaRepressor ProteinsRNA, MessengerTranscription FactorsZen protein, Drosophiladevelopmental biologyD. melanogasterenhancerevolutiongene regulationgeneticsgenomicsHoxproboscipediazen2

Identifiers

PMID32342858
PMCPMC7188484
OpenAlexW3018650767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.