Evidence map›Paper›PMID 32342760›Full record

ArticleJournal of the American Heart Association2020

Sleep Characteristics and Measures of Glucose Metabolism in Blacks: The Jackson Heart Study.

Yuichiro Yano, Yan Gao, Dayna A Johnson, Mercedes Carnethon, Adolfo Correa, Murray A Mittleman, Mario Sims, Elizabeth Mostofsky, James G Wilson, Susan Redline

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Actigraphy-derived sleep fragmentation index: convergent validity and associations with clinical outcomes.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Patterns of Sleep Duration and Metabolic Biomarkers Across the Menstrual Cycle.The Journal of clinical endocrinology and metabolism · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Obesity and Obstructive Sleep Apnea.Handbook of experimental pharmacology · 2022
    Article
  15. Article
  16. Article
  17. Relations of Lifestyle Behavior Clusters to Dyslipidemia in China: A Compositional Data Analysis.International journal of environmental research and public health · 2021
    Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Yuichiro YanoDepartment of Family Medicine and Community Health Duke University Durham NC.
Yan GaoDepartment of Physiology and Biophysics University of Mississippi Medical Center Jackson MS.
Dayna A JohnsonDivision of Sleep and Circadian Disorders Brigham and Women's Hospital Boston MA.
Mercedes CarnethonDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Adolfo CorreaDepartments of Pediatrics and Medicine University of Mississippi Medical Center Jackson MS.
Murray A MittlemanDepartment of Epidemiology Harvard T.H. Chan School 12 of Public Health Boston MA.
Mario SimsDepartments of Pediatrics and Medicine University of Mississippi Medical Center Jackson MS.
Elizabeth MostofskyDepartment of Epidemiology Harvard T.H. Chan School 12 of Public Health Boston MA.
James G WilsonDepartment of Physiology and Biophysics University of Mississippi Medical Center Jackson MS.
Susan RedlineDivision of Sleep and Circadian Disorders Brigham and Women's Hospital Boston MA.
University of Mississippi Medical Center · USBeth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USCircadian (United States) · USDuke University Health System · USHarvard University · USJackson Memorial Hospital · USNorthwestern University · US

Funding

A Mixed Methods Approach for Developing Culturally and Ecologically Appropriate Interventions for Improving Sleep Health in a Community-Based Sample of African Americans.K01HL138211 · NHLBI · EMORY UNIVERSITY · PI JOHNSON, DAYNA · 2017 to 2021
$859k
NHLBI NIH HHS HHSN268201800012CNHLBI NIH HHS HHSN268201800012INHLBI NIH HHS HHSN268201800014CNHLBI NIH HHS HHSN268201800014INHLBI NIH HHS HHSN268201800015INHLBI NIH HHS K01 HL138211NIMHD NIH HHS HHSN268201800013INIMHD NIH HHS L60 MD013236
6 · The paper itself

Abstract

Background Characterizing associations of sleep characteristics with blood-glucose-level factors among blacks may clarify the underlying mechanisms of impaired glucose metabolism and help identify treatment targets to prevent diabetes mellitus in blacks. Methods and Results Cross-sectional analyses were conducted in 789 blacks who completed home sleep apnea testing and 7-day wrist actigraphy in 2012-2016. Sleep-disordered breathing measurements included respiratory event index associated with 4% oxygen desaturation and minimum oxygen saturation. Sleep patterns on actigraphy included fragmented sleep indices. Associations between sleep characteristics (8 exposures) and measures of glucose metabolism (3 outcomes) were determined using multivariable linear regression. Mean (SD) age of the participants was 63 (11) years; 581 (74%) were women; 198 (25%) were diabetes mellitus, and 158 (20%) were taking antihyperglycemic medication. After multivariable adjustment, including antihyperglycemic medication use, the betas (95% CI) for fasting glucose and hemoglobin A1c, respectively, for each SD higher level were 0.13 (0.02, 0.24) mmol/L and 1.11 (0.42, 1.79) mmol/mol for respiratory event index associated with 4% oxygen desaturation and 0.16 (0.05, 0.27) mmol/L and 0.77 (0.10, 1.43) mmol/mol for fragmented sleep indices. Among 589 participants without diabetes mellitus, the betas (95% CI) for homeostatic model assessment of insulin resistance for each SD higher level were 1.09 (1.03, 1.16) for respiratory event index associated with 4% oxygen desaturation, 0.90 (0.85, 0.96) for minimum oxygen saturation, and 1.07 (1.01, 1.13) for fragmented sleep indices. Conclusions Sleep-disordered breathing, overnight hypoxemia, and sleep fragmentation were associated with higher blood glucose levels among blacks.

Indexed as

Black or African AmericanSleepAgedBiomarkersBlood GlucoseCross-Sectional StudiesFemaleGlucose Metabolism DisordersGlycated HemoglobinHumansHypoxiaInsulin ResistanceMaleMiddle AgedMississippiProspective StudiesBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanblacksglucose metabolismsleep

Identifiers

PMID32342760
PMCPMC7428566
OpenAlexW3017866685

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.