Evidence map›Paper›PMID 32342639›Full record

ReviewAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2020

Sensitization in transplantation: Assessment of risk (STAR) 2019 Working Group Meeting Report.

Anat R Tambur, Patricia Campbell, Anita S Chong, Sandy Feng, Mandy L Ford, Howard Gebel, Ronald G Gill, Garnett Kelsoe, Vasilis Kosmoliaptsis, Roslyn B Mannon and 7 more

Abstract readReview
In one paragraph

Review in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. International Society for Heart and Lung Transplantation Scientific Statement on pulmonary antibody-mediated rejection and proposed graft, antibody, and pathology (GAP) definition.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2026
    Guideline
  2. Review
  3. Article
  4. Population-Specific Exploration ofInternational journal of molecular sciences · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Anat R TamburDepartment of Surgery, Comprehensive Transplant Center, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0002-0320-9825
Patricia CampbellDepartment of Laboratory Medicine & Pathology, University of Alberta, Edmonton, Canada.ORCID 0000-0002-1909-4807
Anita S ChongSection of Transplantation, Department of Surgery, The University of Chicago, Chicago, Illinois, USA.ORCID 0000-0003-0460-0196
Sandy FengDepartment of Surgery, UCSF Medical Center, San Francisco, California, USA.
Mandy L FordDepartment of Surgery and Emory Transplant Center, Emory University, Atlanta, Georgia, USA.ORCID 0000-0001-6736-4421
Howard GebelDepartment of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA.
Ronald G GillDepartment of Immunology, University of Colorado, Denver, Colorado, USA.
Garnett KelsoeDepartment of Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Vasilis KosmoliaptsisDepartment of Surgery, University of Cambridge, Cambridge, UK.
Roslyn B MannonDepartment of Medicine, Division of Nephrology, University of Alabama School of Medicine, Birmingham, Alabama, USA.ORCID 0000-0003-1776-3680
Michael MengelDepartment of Laboratory Medicine & Pathology, University of Alberta, Edmonton, Canada.ORCID 0000-0002-7222-3356
Elaine F ReedDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.ORCID 0000-0002-3524-545X
Nicole M ValenzuelaDepartment of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA.ORCID 0000-0003-2024-5382
Chris WiebeDepartment of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0002-1006-3545
I Esme DijkeDepartment of Laboratory Medicine & Pathology, University of Alberta, Edmonton, Canada.
Harold C SullivanDepartment of Pathology, Emory University School of Medicine, Atlanta, Georgia, USA.
Peter NickersonDepartment of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0002-7393-7799

Funding

Department of Health PDF-2016-09-065
6 · The paper itself

Abstract

The purpose of the STAR 2019 Working Group was to build on findings from the initial STAR report to further clarify the expectations, limitations, perceptions, and utility of alloimmune assays that are currently in use or in development for risk assessment in the setting of organ transplantation. The goal was to determine the precision and clinical feasibility/utility of such assays in evaluating both memory and primary alloimmune risks. The process included a critical review of biologically driven, state-of-the-art, clinical diagnostics literature by experts in the field and an open public forum in a face-to-face meeting to promote broader engagement of the American Society of Transplantation and American Society of Histocompatibility and Immunogenetics membership. This report summarizes the literature review and the workshop discussions. Specifically, it highlights (1) available assays to evaluate the attributes of HLA antibodies and their utility both as clinical diagnostics and as research tools to evaluate the effector mechanisms driving rejection; (2) potential assays to assess the presence of alloimmune T and B cell memory; and (3) progress in the development of HLA molecular mismatch computational scores as a potential prognostic biomarker for primary alloimmunity and its application in research trial design.

Indexed as

IsoantibodiesKidney TransplantationGraft RejectionGroup ProcessesHistocompatibilityHLA AntigensHLA AntigensIsoantibodiesalloantibodyantigen biologyclinical research/practicehistocompatibilitylymphocyte biologymajor histocompatibility complex (MHC)rejection: antibody-mediated (ABMR)

Identifiers

PMID32342639
PMCPMC7586936

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.