ReviewAdvances in experimental medicine and biology2020
Exercise and Chronic Pain.
Review in Advances in experimental medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 5 syntheses or guidelines pooled it, 96 citations in OpenAlex.
- Efficacy of home-based exercise in the treatment of pain and disability at the hip and knee in patients with osteoarthritis: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2024Pooled it
- Telerehabilitation as a Therapeutic Exercise Tool versus Face-to-Face Physiotherapy: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- Correlation between the Altered Gut Microbiome and Lifestyle Interventions in Chronic Widespread Pain Patients: A Systematic Review.Medicina (Kaunas, Lithuania) · 2023Pooled it
- Sensorimotor Integration and Pain Perception: Mechanisms Integrating Nociceptive Processing. A Systematic Review and ALE-Meta Analysis.Frontiers in integrative neuroscience · 2022Pooled it
- Baduanjin exercise: A potential promising therapy toward osteoporosis.Frontiers in medicine · 2022Pooled it
- Videoconference-Supervised Group Exercise Reduces Low Back Pain in Eldercare Workers: Results from the ReViEEW Randomised Controlled Trial.Journal of occupational rehabilitation · 2025Trial
- Rehabilitation therapy using the HUBER platform in chronic non-specific low back pain: a randomized controlled trial.European journal of physical and rehabilitation medicine · 2023Trial
- Kinesiophobia could affect shoulder function after repair of rotator cuff tears.BMC musculoskeletal disorders · 2022Trial
- Sustained relief of chronic headache using percutaneous 60-day peripheral nerve stimulation treatment: 12-month results from a multicenter, prospective clinical study.Interventional pain medicine · 2026Article
- Kinesiophobia and its impact on shoulder function in patients following arthroscopic rotator cuff repair of the supraspinatus tendon: a cross-sectional study.BMC musculoskeletal disorders · 2026Article
- Cardiorespiratory fitness and pain severity: Longitudinal associations from the general population-The HUNT study.Pain reports · 2026Article
- Beyond Symptom Reduction: A Qualitative Study of Refugees' Experiences of a Trauma-Informed Community-Based Pain Management Program.European journal of pain (London, England) · 2026Article
- Physical Activity for Human and Planetary Health: Incorporating Green Exercise in the Management of Rheumatic Disease.Rheumatic diseases clinics of North America · 2026Review
- Dual-Site Pain in the Low Back and Knee as a Risk Factor for Dementia: A Population-Based Cohort Study.Journal of pain research · 2026Article
- Effectiveness of Bowen Therapy for Fibromyalgia: A Randomized Controlled Trial.International journal of therapeutic massage & bodywork · 2025Article
- Platelet-Rich Plasma for Treating Chronic Noncancer Pain: A Systematic Review and Meta-analysis of Randomized Controlled Trials.Pain and therapy · 2025Review
- Differential relationships between physical activity and pain phenotypes in individuals with spinal cord injury.The journal of spinal cord medicine · 2025Observational
- Associations Between Pain Intensity and Inflammatory Profile in Women with Android and Gynoid Obesity Diagnosed with Chronic Pain: An Observational Study.Journal of clinical medicine · 2025Article
- Clinical Benefits of Ibuprofen Arginine: A Narrative Review.Pain and therapy · 2025Review
- Comparison of Temporomandibular Disorder Signs and Symptoms in CrossFitInternational journal of environmental research and public health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this chapter, we describe the impact and etiology of chronic pain, the associated changes in the nervous system, and the mechanisms by which exercise may be able to affect and reverse these changes. Evidence for efficacy of exercise in different conditions associated with chronic pain is presented, with focus on chronic low back pain, fibromyalgia, osteoarthritis, rheumatoid arthritis, and migraines. While the efficacy of exercise and level of evidence supporting it vary in different diseases, exercise has direct and indirect benefits for most patients suffering from chronic pain. Effective exercise regimens include education and cognitive restructuring to promote behavioral activation and reconceptualization of what pain means, with the goal of gradually reversing the vicious cycle of pain, inertia, sedentary behavior, and worsening disability. Long-term, consistent, individualized exercise-based treatment approaches are most likely to result in improvements in pain and function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.