Evidence map›Paper›PMID 32342433›Full record

ArticleMolecular biology reports2020

Multiple omics analysis of the protective effects of SFN on estrogen-dependent breast cancer cells.

Hui Huang, Shuyuan Cao, Zhan Zhang, Lei Li, Feng Chen, Qian Wu

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hui HuangDepartment of Biostatistics and China International Cooperation Center for Environment and Human Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Shuyuan CaoDepartment of Hygienic Analysis and the Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Zhan ZhangDepartment of Hygienic Analysis and the Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Lei LiDepartment of Hygienic Analysis and the Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Feng ChenDepartment of Biostatistics and China International Cooperation Center for Environment and Human Health, School of Public Health, Nanjing Medical University, Nanjing, 211166, China. fengchen@njmu.edu.cn.
Qian WuDepartment of Hygienic Analysis and the Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, 211166, China. wuqian@njmu.edu.cn.
Nanjing Medical University · CN

Funding

National Natural Science Foundation of China 81728018National Natural Science Foundation of China 81903365National Natural Science Foundation of China (CN) 81530088Natural Science Foundation of Jiangsu Province BK20161571Natural Science Foundation of the Jiangsu Higher Education Institution of China 16KJA330002
6 · The paper itself

Abstract

In recent years, sulforaphane (SFN) has been shown to have antitumor effects. To better understand the molecular basis of SFN intervention in estrogen-dependent breast cancer, integrated multi-omics data analysis was used to provide evidence and insights into molecular biology. MCF-7 breast cancer cells were treated with estradiol (E

Indexed as

Breast NeoplasmsChromatography, LiquidDNADNA MethylationEstradiolEstrogensFemaleGene ExpressionGene Expression Regulation, NeoplasticHumansIsothiocyanatesMCF-7 CellsSulfoxidesTandem Mass SpectrometryDNAEstradiolEstrogensIsothiocyanatessulforaphaneSulfoxidesBreast cancerDNA methylationMetaboliteProteinSulforaphane

Identifiers

PMID32342433
OpenAlexW3017885471

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.