ArticleClinical and experimental nephrology2020
The clinical characteristic and outcome of skin and soft tissue infection in immunosuppressive patients with nephrotic syndrome.
Article in Clinical and experimental nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Hospital acquired drug resistant pathogens infections in patients with viral respiratory tract infections: a retrospective study.BMC infectious diseases · 2025Article
- Diagnostic Challenge: Prolonged Misdiagnosis of Perianal Herpes in an Immunosuppressed Transplant Patient.Clinical, cosmetic and investigational dermatology · 2025Article
- Maxillary herpes zoster with nasociliary nerve involvement andClinical case reports · 2024Article
- Atypical facial pustular folliculitis byDermatology reports · 2024Article
- Predicting bacterial infection risk in patients with ANCA-associated vasculitis in southwest China: development of a new nomogram.Clinical rheumatology · 2022Article
- COVID-19 Severity among Healthcare Workers: Overweight Male Physicians at Risk.Infectious disease reports · 2022Article
- Skin and soft tissue infection suspiciously caused byMedicine internationalArticle
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Authors and funding
5 authors.
Funding
Abstract
objectiveSkin and soft tissue infection (SSTI) is the most common of infectious diseases with high morbidity and mortality. However, the clinical characteristics of SSTI in patients with nephrotic syndrome (NS), especially in those patients who received immunosuppressive therapy, are still lacking. The present study was conducted to investigate the clinical characteristics and outcomes of SSTI in patients with NS.
methodsA retrospective study was carried out among the patients diagnosed with NS and SSTI, who have priorly received or currently have been receiving immunosuppressive therapy between April 2011 and January 2019; the clinical profile included patient's baseline characteristics, clinical presentation, microbiological findings, treatment, and prognosis.
resultsA total of 70 patients were analyzed. Results showed that more than half of the patients were under 35 years old, and moderate infection was the most common type of SSTI. Leg and cellulitis were the most common site of lesion and the typical clinical manifestation of SSTI, respectively. Patients in the severe infection group have a higher level of procalcitonin (PCT) and C-reactive protein (CRP), while a lower level of albumin, CD4
conclusionsPatients with NS and SSTI usually showed a satisfying outcome with proper anti-infection treatment, but severe SSTI can be life-threatening.
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