Evidence map›Paper›PMID 32342255›Full record

ArticleInternational ophthalmology2020

Combined aspirin and clopidogrel therapy in phacoemulsification cataract surgery: a risk factor for ocular hemorrhage?

Qingjian Li, Xuzhong Shen, Shaopan Wang, Ting Su, Ke Yan, Yu Zhang, Yiwen Qian, Jing Jiang, Pei Zhang, Zhiliang Wang

Abstract read
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In one paragraph

Article in International ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Qingjian LiEye Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Xuzhong ShenDepartment of Ophthalmology, Huashan Hospital, Fudan University, No. 12 Middle Urumqi Road, Shanghai, 200040, China.
Shaopan WangEye Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Ting SuEye Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Ke YanEye Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Yu ZhangDepartment of Ophthalmology, Huashan Hospital, Fudan University, No. 12 Middle Urumqi Road, Shanghai, 200040, China.
Yiwen QianDepartment of Ophthalmology, Huashan Hospital, Fudan University, No. 12 Middle Urumqi Road, Shanghai, 200040, China.
Jing JiangDepartment of Ophthalmology, Huashan Hospital, Fudan University, No. 12 Middle Urumqi Road, Shanghai, 200040, China.
Pei ZhangDepartment of Ophthalmology, Shanghai Gonghui Hospital, No. 6, Lane 315, Shimen Road (No. 1), Shanghai, 200040, China. zhangpei7607@163.com.
Zhiliang WangDepartment of Ophthalmology, Huashan Hospital, Fudan University, No. 12 Middle Urumqi Road, Shanghai, 200040, China. ophwzl@163.com.ORCID http://orcid.org/0000-0003-0944-8584
Fudan University · CNXiamen University · CNShanghai Zhabei District Shibei Hospital · CN

Funding

Natural Science Foundation of China 81670868Natural Science Foundation of China 81900879
6 · The paper itself

Abstract

purposeTo evaluate the safety of phacoemulsification cataract surgery in the patients undergoing dual antiplatelet therapy with aspirin and clopidogrel.

methodsConsecutive patients undergoing phacoemulsification cataract surgery with a clear corneal incision under topical anesthesia were eligible for inclusion in the study. Thirty-eight eyes from 38 patients on combined aspirin and clopidogrel therapy who continued the treatment were classified into the maintenance group, a matched group of 38 eyes from 38 patients on no antiplatelet/anticoagulant therapy as the control group. The best-corrected visual acuity (BCVA) and incidences of complications were compared between the two groups.

resultsThere was no significant difference in final BCVA between the maintenance group and the control group (p = 0.178). No significant difference existed in the incidences of hemorrhagic or non-hemorrhagic complications between the two groups (p = 0.529 and p = 0.589, respectively). Moreover, no surgery was postponed or cancelled due to hemorrhagic complications in either group, and no cardiovascular events occurred during the follow-up. There was no case of anterior chamber hemorrhage, vitreous hemorrhage, or suprachoroidal hemorrhage.

conclusionsOur outcomes indicated that phacoemulsification cataract surgery using a clear corneal incision with topical anesthesia could be safely done without stopping dual antiplatelet therapy with aspirin and clopidogrel.

Indexed as

CataractPhacoemulsificationAspirinClopidogrelHumansLens Implantation, IntraocularPostoperative ComplicationsRisk FactorsVisual AcuityAspirinClopidogrelAspirinCataract surgeryClopidogrelComplicationsTopical anesthesia

Identifiers

PMID32342255
OpenAlexW3019960840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.