Evidence map›Paper›PMID 32342191›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2020

FDG-PET/CT findings highly suspicious for COVID-19 in an Italian case series of asymptomatic patients.

Lucia Setti, Margarita Kirienko, Serena Camilla Dalto, Manuela Bonacina, Emilio Bombardieri

Open access · bronzeAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Incidental Findings Suggestive of COVID-19 Pneumonia in Oncologic Patients UndergoingJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  10. Article
  11. Review
  12. Asia Oceania journal of nuclear medicine & biology · 2022
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Prevalence of interstitial pneumonia suggestive of COVID-19 atEuropean journal of nuclear medicine and molecular imaging · 2021
    Observational
  18. Differences among [Scientific reports · 2021
    Article
  19. Imaging of COVID-19: CT, MRI, and PET.Seminars in nuclear medicine · 2021
    Review
  20. A comprehensive review of imaging findings in COVID-19 - status in early 2021.European journal of nuclear medicine and molecular imaging · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lucia SettiNuclear Medicine Unit, Humanitas Gavazzeni, Bergamo, Italy.
Margarita KirienkoNuclear Medicine Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy. margarita.kirienko@icloud.com.ORCID 0000-0002-3923-1151
Serena Camilla DaltoClinical Oncology Unit, Humanitas Gavazzeni, Bergamo, Italy.
Manuela BonacinaNuclear Medicine Unit, Humanitas Gavazzeni, Bergamo, Italy.
Emilio BombardieriNuclear Medicine Unit, Humanitas Gavazzeni, Bergamo, Italy.
Humanitas Gavazzeni · ITFondazione IRCCS Istituto Nazionale dei Tumori · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo illustrate the [18F]FDG-PET/CT findings in patients affected by cancer with clinical diagnosis of Covid-19

methodsWe retrospectively reviewed the cases of patients who showed pulmonary involvement unrelated to cancer metastases on March 13 and 16 2020. We reviewed the scans, collected medical history, and exposure information.

resultsAmong the 13 scans, we identified 5 cases with imaging findings suspicious for viral infection. Peripheral lung consolidations and/or ground-glass opacities in two or more lobes were found. Lung abnormalities displayed increased [18F]FDG uptake (SUVmax 4.3-11.3). All the patients on the day of PET/CT acquisition were asymptomatic, and they did not have fever or cough. In view of the PET/CT findings, home isolation, symptom surveillance, and treatment (in 3/5 patients) were indicated. At 1-week follow-up, 2/5 patients experienced the onset of mild respiratory symptoms.

conclusionsThe [18F]FDG-PET/CT can identify probable Covid-19 disease in the absence or before symptoms onset and can guide patient management. Nuclear medicine staff needs to be aware of the possibility of contact with patients affected by the SARS-CoV-2 infection even if they do not present any symptom. Therefore, safety measures need to be adopted for other patients and hospital staff in order to block the spread of infection.

Indexed as

BetacoronavirusCoronavirus InfectionsCOVID-19Equipment and SuppliesFluorodeoxyglucose F18HumansItalyLungPandemicsPatient SafetyPneumonia, ViralPositron Emission Tomography Computed TomographyRetrospective StudiesSARS-CoV-2Fluorodeoxyglucose F18AsymptomaticCoronavirusCOVID-19FDG-PET/CTImagingSARS-CoV-2

Identifiers

PMID32342191
PMCPMC7184819
OpenAlexW3019210634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.