Evidence map›Paper›PMID 32342021›Full record

ArticleJournal of the Endocrine Society2020

In Vitro Impact of FSH Glycosylation Variants on FSH Receptor-stimulated Signal Transduction and Functional Selectivity.

Teresa Zariñán, Viktor Y Butnev, Rubén Gutiérrez-Sagal, José Luis Maravillas-Montero, Iván Martínez-Luis, Nancy R Mejía-Domínguez, Guillermo Juárez-Vega, George R Bousfield, Alfredo Ulloa-Aguirre

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
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  10. Review
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  12. Human FSH Glycoform α-Subunit AsparagineFrontiers in endocrinology · 2022
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Follicle-Stimulating Hormone Induces Lipid DropletsFrontiers in endocrinology · 2021
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Teresa ZariñánRed de Apoyo a la Investigación (RAI), Universidad Nacional Autónoma de México (UNAM)-Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Viktor Y ButnevDepartment of Biological Sciences, Wichita State University, Wichita, Kansas, USA.
Rubén Gutiérrez-SagalRed de Apoyo a la Investigación (RAI), Universidad Nacional Autónoma de México (UNAM)-Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
José Luis Maravillas-MonteroRed de Apoyo a la Investigación (RAI), Universidad Nacional Autónoma de México (UNAM)-Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Iván Martínez-LuisRed de Apoyo a la Investigación (RAI), Universidad Nacional Autónoma de México (UNAM)-Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Nancy R Mejía-DomínguezRed de Apoyo a la Investigación (RAI), Universidad Nacional Autónoma de México (UNAM)-Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Guillermo Juárez-VegaRed de Apoyo a la Investigación (RAI), Universidad Nacional Autónoma de México (UNAM)-Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
George R BousfieldDepartment of Biological Sciences, Wichita State University, Wichita, Kansas, USA.
Alfredo Ulloa-AguirreRed de Apoyo a la Investigación (RAI), Universidad Nacional Autónoma de México (UNAM)-Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.ORCID 0000-0002-9532-3886
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXWichita State University · US

Funding

The Aging Pituitary/Gonadal AxisP01AG029531 · NIA · WICHITA STATE UNIVERSITY · PI CHITTIBABU GUDA · 2009 to 2026
$25.9M
NIA NIH HHS P01 AG029531
6 · The paper itself

Abstract

FSH exists as different glycoforms that differ in glycosylation of the hormone-specific β-subunit. Tetra-glycosylated FSH (FSH

Indexed as

biased agonismfollicle-stimulating hormonefollicle-stimulating hormone receptorfunctional selectivityglycosylationmacroheterogeneitysignal transduction

Identifiers

PMID32342021
PMCPMC7175721
OpenAlexW3007787571

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.