Evidence map›Paper›PMID 32341757›Full record

ArticleOncotarget2020

Targeted alpha therapy using astatine (

Tadashi Watabe, Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuwei Liu, Kazuhiro Ooe, Takahiro Teramoto, Atsushi Toyoshima, Eku Shimosegawa, Takashi Nakano, Yoshikatsu Kanai and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. L-3-[International journal of molecular sciences · 2025
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. AnEuropean journal of nuclear medicine and molecular imaging · 2025
    Article
  7. Enhancing the Stability ofACS medicinal chemistry letters · 2025
    Article
  8. Review
  9. Article
  10. Evaluation of Targeted Alpha Therapy Using [International journal of molecular sciences · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Targeted α-therapy using astatine (European journal of nuclear medicine and molecular imaging · 2023
    Article
  17. Study ofMaterials (Basel, Switzerland) · 2022
    Article
  18. Article
  19. Production Review of Accelerator-Based Medical Isotopes.Molecules (Basel, Switzerland) · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Tadashi WatabeDepartment of Nuclear Medicine and Tracer Kinetics, Graduate School of Medicine, Osaka University, Suita, Japan.
Kazuko Kaneda-NakashimaInstitute for Radiation Sciences, Osaka University, Suita, Japan.
Yoshifumi ShirakamiInstitute for Radiation Sciences, Osaka University, Suita, Japan.
Yuwei LiuDepartment of Nuclear Medicine and Tracer Kinetics, Graduate School of Medicine, Osaka University, Suita, Japan.
Kazuhiro OoeDepartment of Nuclear Medicine and Tracer Kinetics, Graduate School of Medicine, Osaka University, Suita, Japan.
Takahiro TeramotoInstitute for Radiation Sciences, Osaka University, Suita, Japan.
Atsushi ToyoshimaInstitute for Radiation Sciences, Osaka University, Suita, Japan.
Eku ShimosegawaInstitute for Radiation Sciences, Osaka University, Suita, Japan.
Takashi NakanoInstitute for Radiation Sciences, Osaka University, Suita, Japan.
Yoshikatsu KanaiDepartment of Bio-system Pharmacology, Graduate School of Medicine, Osaka University, Suita, Japan.
Atsushi ShinoharaInstitute for Radiation Sciences, Osaka University, Suita, Japan.
Jun HatazawaInstitute for Radiation Sciences, Osaka University, Suita, Japan.
Osaka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenylalanine derivatives, which target tumors especially through L-type amino acid transporter-1 (LAT1), have elicited considerable attention. In this study, we evaluated the treatment effect of phenylalanine labeled with the alpha emitter astatine (

Indexed as

alpha therapyastatinegliomaLAT1phenylalanine

Identifiers

PMID32341757
PMCPMC7170498
OpenAlexW3016674508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.