Evidence map›Paper›PMID 32341562›Full record

ArticleNature biotechnology2020

Plants with genetically encoded autoluminescence.

Tatiana Mitiouchkina, Alexander S Mishin, Louisa Gonzalez Somermeyer, Nadezhda M Markina, Tatiana V Chepurnyh, Elena B Guglya, Tatiana A Karataeva, Kseniia A Palkina, Ekaterina S Shakhova, Liliia I Fakhranurova and 17 more

Erratum issuedAbstract read
In one paragraph

Article in Nature biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
  6. Sentinel plants enable quantitative monitoring of bioavailable nitrate in soils and microbial environments.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Bioluminescence in the Edible MushroomJournal of fungi (Basel, Switzerland) · 2026
    Article
  8. Article
  9. The Promise of Synthetic Biology for Redesigning Plant Architecture.International journal of molecular sciences · 2026
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Synthesis of large single-transcript pathways from oligonucleotide pools: Design of STARBURST, an autobioluminescent reporter.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  20. Review

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors.

Tatiana Mitiouchkina *Planta LLC, Moscow, Russia.
Alexander S Mishin *Planta LLC, Moscow, Russia.ORCID http://orcid.org/0000-0002-4935-7030
Louisa Gonzalez Somermeyer *Institute of Science and Technology Austria, Klosterneuburg, Austria.ORCID http://orcid.org/0000-0001-9139-5383
Nadezhda M Markina *Planta LLC, Moscow, Russia.
Tatiana V ChepurnyhPlanta LLC, Moscow, Russia.
Elena B GuglyaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Tatiana A KarataevaPlanta LLC, Moscow, Russia.
Kseniia A PalkinaPlanta LLC, Moscow, Russia.
Ekaterina S ShakhovaPlanta LLC, Moscow, Russia.
Liliia I FakhranurovaPlanta LLC, Moscow, Russia.
Sofia V ChekovaPlanta LLC, Moscow, Russia.
Aleksandra S TsarkovaPlanta LLC, Moscow, Russia.
Yaroslav V GolubevPirogov Russian National Research Medical University, Moscow, Russia.
Vadim V NegrebetskyPirogov Russian National Research Medical University, Moscow, Russia.
Sergey A DolgushinAivok LLC, Zelenograd, Moscow, Russia.
Pavel V ShalaevAivok LLC, Zelenograd, Moscow, Russia.
Dmitry ShlykovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Olesya A MelnikPlanta LLC, Moscow, Russia.
Victoria O ShipunovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Sergey M DeyevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Andrey I BubyrevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Alexander S PushinPlanta LLC, Moscow, Russia.
Vladimir V ChoobBotanical Garden of Lomonosov Moscow State University, Moscow, Russia.
Sergey V DolgovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Fyodor A KondrashovInstitute of Science and Technology Austria, Klosterneuburg, Austria.
Ilia V Yampolsky *Planta LLC, Moscow, Russia. ivyamp@gmail.com.
Karen S Sarkisyan *Planta LLC, Moscow, Russia. karen@planta.bio.ORCID http://orcid.org/0000-0002-5375-6341

Funding

Medical Research Council MC-A658-5QEA0Medical Research Council MC_UP_1605/9
6 · The paper itself

Abstract

Autoluminescent plants engineered to express a bacterial bioluminescence gene cluster in plastids have not been widely adopted because of low light output. We engineered tobacco plants with a fungal bioluminescence system that converts caffeic acid (present in all plants) into luciferin and report self-sustained luminescence that is visible to the naked eye. Our findings could underpin development of a suite of imaging tools for plants.

Indexed as

Caffeic AcidsFirefly LuciferinFungiNicotianaPlants, Genetically Modifiedcaffeic acidCaffeic AcidsFirefly Luciferin

Identifiers

PMID32341562
PMCPMC7610436

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.