ArticleScientific reports2020
Dynamic network properties of the interictal brain determine whether seizures appear focal or generalised.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Directed graph neural networks with partial directed coherence for seizure prediction and epileptogenic network characterization.iScience · 2026Article
- Population-based spectral characteristics of normal interictal scalp EEG inform diagnosis and treatment planning in focal epilepsy.Scientific reports · 2025Article
- The Value of Normal Interictal EEGs in Epilepsy Diagnosis and Treatment Planning: A Retrospective Cohort Study using Population-level Spectral Power and Connectivity Patterns.medRxiv : the preprint server for health sciences · 2025Article
- Precision neuromodulation in epilepsy: from shared targets to personalized circuits.Brain communications · 2025Article
- Optimising anti-seizure medication timing using a dynamic network model of seizure rhythms.Frontiers in network physiology · 2025Article
- Associating EEG functional networks and the effect of sleep deprivation as measured using psychomotor vigilance tests.Scientific reports · 2024Article
- The impact of paediatric epilepsy and co-occurring neurodevelopmental disorders on functional brain networks in wake and sleep.PloS one · 2024Article
- Case Report: Focal, generalized, or both: does generalized network involvement preclude successful epilepsy surgery?Frontiers in network physiology · 2024Article
- Machine-learning for the prediction of one-year seizure recurrence based on routine electroencephalography.Scientific reports · 2023Article
- Resting state functional connectivity demonstrates increased segregation in bilateral temporal lobe epilepsy.Epilepsia · 2023Article
- The time-evolving epileptic brain network: concepts, definitions, accomplishments, perspectives.Frontiers in network physiology · 2023Review
- Machine learning and clinical neurophysiology.Journal of neurology · 2022Article
- Quantitative analysis of visually reviewed normal scalp EEG predicts seizure freedom following anterior temporal lobectomy.Epilepsia · 2022Article
- Modulations of local synchrony over time lead to resting-state functional connectivity in a parsimonious large-scale brain model.PloS one · 2022Article
- A large-scale brain network mechanism for increased seizure propensity in Alzheimer's disease.PLoS computational biology · 2021Article
- Characterizing the electrophysiological abnormalities in visually reviewed normal EEGs of drug-resistant focal epilepsy patients.Brain communications · 2021Article
- Increased facial asymmetry in focal epilepsies associated with unilateral lesions.Brain communications · 2021Article
- Phase and amplitude dynamics of coupled oscillator systems on complex networks.Chaos (Woodbury, N.Y.) · 2020Article
- Domino-like transient dynamics at seizure onset in epilepsy.PLoS computational biology · 2020Article
- Artificial Intelligence and Computational Approaches for Epilepsy.Journal of epilepsy research · 2020Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Current explanatory concepts suggest seizures emerge from ongoing dynamics of brain networks. It is unclear how brain network properties determine focal or generalised seizure onset, or how network properties can be described in a clinically-useful manner. Understanding network properties would cast light on seizure-generating mechanisms and allow to quantify to which extent a seizure is focal or generalised. Functional brain networks were estimated in segments of scalp-EEG without interictal discharges (68 people with epilepsy, 38 controls). Simplified brain dynamics were simulated using a computer model. We introduce: Critical Coupling (C
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Registered trials
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