Evidence map›Paper›PMID 32341346›Full record

ArticleNature communications2020

The phylogenetic landscape and nosocomial spread of the multidrug-resistant opportunist Stenotrophomonas maltophilia.

Matthias I Gröschel, Conor J Meehan, Ivan Barilar, Margo Diricks, Aitor Gonzaga, Matthias Steglich, Oscar Conchillo-Solé, Isabell-Christin Scherer, Uwe Mamat, Christian F Luz and 21 more

Abstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed.

  1. Clinical, microbiological, and molecular characteristics, outcomes, and risk factors for mortality of patients with Stenotrophomonas maltophilia bloodstream infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
  3. Article
  4. Antibiotics (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Integrated genomic analysis ofFrontiers in microbiology · 2026
    Article
  11. Infection and drug resistance · 2026
    Review
  12. Article
  13. Draft genome sequence ofMicrobiology resource announcements · 2025
    Article
  14. Virulence · 2025
    Article
  15. Article
  16. Comparative Analyses Suggest Genome Stability and Plasticity inInternational journal of molecular sciences · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Evidence of dissemination of aAntimicrobial agents and chemotherapy · 2025
    Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Matthias I GröschelMolecular and Experimental Mycobacteriology, Research Center Borstel, Borstel, Germany.ORCID http://orcid.org/0000-0002-2509-3034
Conor J MeehanSchool of Chemistry and Bioscience, University of Bradford, Bradford, United Kingdom.ORCID http://orcid.org/0000-0003-0724-8343
Ivan BarilarMolecular and Experimental Mycobacteriology, Research Center Borstel, Borstel, Germany.ORCID http://orcid.org/0000-0002-4789-2777
Margo DiricksbioMérieux, Applied Maths NV, Keistraat 120, 9830, St-Martens-Latem, Belgium.ORCID http://orcid.org/0000-0002-5428-1456
Aitor GonzagaLeibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Matthias SteglichLeibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Oscar Conchillo-SoléInstitute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0003-4266-246X
Isabell-Christin SchererDepartment of Infectious Diseases and Microbiology, University Hospital Schleswig-Holstein, Lübeck, Germany.
Uwe MamatCellular Microbiology, Research Center Borstel, Borstel, Germany.
Christian F LuzDepartment of Medical Microbiology and Infection Prevention, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0001-5809-5995
Katrien De BruynebioMérieux, Applied Maths NV, Keistraat 120, 9830, St-Martens-Latem, Belgium.
Christian UtpatelMolecular and Experimental Mycobacteriology, Research Center Borstel, Borstel, Germany.
Daniel YeroInstitute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0002-6234-4082
Isidre GibertInstitute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0003-1442-2258
Xavier DauraInstitute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0001-9235-6730
Stefanie KampmeierInstitute of Hygiene, University Hospital Münster, Münster, Germany.
Nurdyana Abdul RahmanDepartment of Microbiology, Singapore General Hospital, Singapore, Singapore.
Michael KreskenAntiinfectives Intelligence GmbH, Rheinbach, Germany.
Tjip S van der WerfDepartment of Pulmonary Diseases & Tuberculosis, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-4824-1642
Ifey AlioDepartment of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany.
Wolfgang R StreitDepartment of Microbiology and Biotechnology, University of Hamburg, Hamburg, Germany.ORCID http://orcid.org/0000-0001-7617-7396
Kai ZhouShenzhen Institute of Respiratory Diseases, the First Affiliated Hospital (Shenzhen People's Hospital), Southern University of Science and Technology, Shenzhen, China.
Thomas SchwartzKarlsruhe Institute of Technology, Institute of Functional Interfaces, Eggenstein- Leopoldshafen, Germany.ORCID http://orcid.org/0000-0001-7372-4729
John W A RossenDepartment of Medical Microbiology and Infection Prevention, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-7167-8623
Maha R FarhatDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-3871-5760
Ulrich E SchaibleCellular Microbiology, Research Center Borstel, Borstel, Germany.ORCID http://orcid.org/0000-0002-6638-7282
Ulrich NübelLeibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.ORCID http://orcid.org/0000-0003-3131-1656
Jan RuppDepartment of Infectious Diseases and Microbiology, University Hospital Schleswig-Holstein, Lübeck, Germany.ORCID http://orcid.org/0000-0001-8722-1233
Joerg SteinmannInstitute of Medical Microbiology, University Medical Center Essen, Essen, Germany.
Stefan NiemannMolecular and Experimental Mycobacteriology, Research Center Borstel, Borstel, Germany. sniemann@fz-borstel.de.
Thomas A KohlMolecular and Experimental Mycobacteriology, Research Center Borstel, Borstel, Germany.ORCID http://orcid.org/0000-0002-1126-6803

Funding

New Tools for the interpretation of Pathogen Genomic Data with a focus on Mycobacterium tuberculosisK01ES026835 · NIEHS · MASSACHUSETTS GENERAL HOSPITAL · PI FARHAT, MAHA · 2015 to 2019
$1.1M
NIEHS NIH HHS K01 ES026835
6 · The paper itself

Abstract

Recent studies portend a rising global spread and adaptation of human- or healthcare-associated pathogens. Here, we analyse an international collection of the emerging, multidrug-resistant, opportunistic pathogen Stenotrophomonas maltophilia from 22 countries to infer population structure and clonality at a global level. We show that the S. maltophilia complex is divided into 23 monophyletic lineages, most of which harbour strains of all degrees of human virulence. Lineage Sm6 comprises the highest rate of human-associated strains, linked to key virulence and resistance genes. Transmission analysis identifies potential outbreak events of genetically closely related strains isolated within days or weeks in the same hospitals.

Indexed as

AllelesAnti-Bacterial AgentsCluster AnalysisCross InfectionDrug Resistance, Multiple, BacterialGenome, BacterialGeographyGram-Negative Bacterial InfectionsHumansOpportunistic InfectionsPhylogenyStenotrophomonas maltophiliaVirulenceAnti-Bacterial Agents

Identifiers

PMID32341346
PMCPMC7184733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.