Evidence map›Paper›PMID 32341343›Full record

ArticleNature communications2020

Cytokines regulate the antigen-presenting characteristics of human circulating and tissue-resident intestinal ILCs.

Anna Rao, Otto Strauss, Efthymia Kokkinou, Mélanie Bruchard, Kumar P Tripathi, Heinrich Schlums, Anna Carrasco, Luca Mazzurana, Viktoria Konya, Eduardo J Villablanca and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Resisting Resistance to Immune Checkpoint Therapy: A Systematic Review.International journal of molecular sciences · 2020
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Immunological mechanisms of autoimmune gastritis.Clinical and experimental medicine · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Innate Lymphoid Cells.Advances in experimental medicine and biology · 2025
    Review
  18. Review
  19. The emerging family of RORγtNature reviews. Immunology · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Anna RaoCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden. anna.rao@ki.se.
Otto Strauss *Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.
Efthymia Kokkinou *Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.
Mélanie BruchardDepartment of Experimental Immunology, Academic Medical Center at the University of Amsterdam, Amsterdam, Netherlands.
Kumar P TripathiImmunology and Allergy Division, Department of Medicine, Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, 17164, Sweden.
Heinrich SchlumsCenter for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Anna CarrascoCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.
Luca MazzuranaCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.
Viktoria KonyaCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.
Eduardo J VillablancaImmunology and Allergy Division, Department of Medicine, Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, 17164, Sweden.ORCID http://orcid.org/0000-0001-9522-9729
Niklas K BjörkströmCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-0967-076X
Ulrik LindforssDepartment of Molecular Medicine and Surgery, Karolinska Institutet and Center for Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden.
Hergen SpitsDepartment of Experimental Immunology, Academic Medical Center at the University of Amsterdam, Amsterdam, Netherlands.ORCID http://orcid.org/0000-0003-3269-8338
Jenny MjösbergCenter for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden. jenny.mjosberg@ki.se.
Karolinska University Hospital · SEAmsterdam UMC Location University of Amsterdam · NLKarolinska Institutet · SELinköping University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ILCs and T helper cells have been shown to exert bi-directional regulation in mice. However, how crosstalk between ILCs and CD4

Indexed as

Immunity, InnateAnimalsAntigen PresentationAntigen-Presenting CellsCD4-Positive T-LymphocytesColonic NeoplasmsCytokinesHumansInflammasomesInterleukin-18Interleukin-1betaIntestinal MucosaLeukocytes, MononuclearLymphocytesMiceCytokinesIL18 protein, humanIL1B protein, humanInflammasomesInterleukin-18Interleukin-1beta

Identifiers

PMID32341343
PMCPMC7184749
OpenAlexW3019084337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.