Evidence map›Paper›PMID 32341126›Full record

ArticleThe Journal of biological chemistry2020

Targeting a critical step in fungal hexosamine biosynthesis.

Deborah E A Lockhart, Mathew Stanley, Olawale G Raimi, David A Robinson, Dominika Boldovjakova, Daniel R Squair, Andrew T Ferenbach, Wenxia Fang, Daan M F van Aalten

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 27 citations in OpenAlex.

  1. Analysis of the Subculture Effect on theJournal of fungi (Basel, Switzerland) · 2026
    Article
  2. Compromising UDP-sugar nucleotide biosynthesis attenuatesCell surface (Amsterdam, Netherlands) · 2026
    Article
  3. Article
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  6. Fungal Chitin Synthases: Structure, Function, and Regulation.Journal of fungi (Basel, Switzerland) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Deborah E A LockhartSchool of Life Sciences, University of Dundee, Dundee, United Kingdom; Institute of Medical Sciences, Foresterhill, University of Aberdeen, Aberdeen, United Kingdom. Electronic address: deborah.lockhart@abdn.ac.uk.
Mathew StanleySchool of Life Sciences, University of Dundee, Dundee, United Kingdom.
Olawale G RaimiSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.
David A RobinsonDrug Discovery Unit, Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Dominika BoldovjakovaInstitute of Medical Sciences, Foresterhill, University of Aberdeen, Aberdeen, United Kingdom.
Daniel R SquairSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.
Andrew T FerenbachSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.
Wenxia FangSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.
Daan M F van AaltenSchool of Life Sciences, University of Dundee, Dundee, United Kingdom. Electronic address: dmfvanaalten@dundee.ac.uk.
University of Dundee · GBUniversity of Aberdeen · GB

Funding

Medical Research Council MR/M004139/1Wellcome TrustWellcome Trust WT105772/A/14/ZWellcome Trust WT105772/Z/14/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntifungal AgentsAspergillosisAspergillus fumigatusBiosynthetic PathwaysCatalytic DomainCell WallChitinCrystallography, X-RayGlucosamine 6-Phosphate N-AcetyltransferaseHexosaminesMaleMiceModels, MolecularMolecular Targeted TherapyProtein ConformationAntifungal AgentsChitinGlucosamine 6-Phosphate N-AcetyltransferaseHexosaminesSmall Molecule Librariesantifungal drug developmentAspergillus fumigatuscell wallchitinfragmentfungiglucosamine 6-phosphate N-acetyltransferase (Gna1)protein-protein interactionresistancevirulence factorX-ray crystallography

Identifiers

PMID32341126
PMCPMC7324522
OpenAlexW3017557457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.