Evidence map›Paper›PMID 32340990›Full record

ArticleAntimicrobial agents and chemotherapy2020

Emergence of Mycobacterium leprae Rifampin Resistance Evaluated by Whole-Genome Sequencing after 48 Years of Irregular Treatment.

Charlotte Avanzi, Raquel Cristina Maia, Andrej Benjak, José Augusto Nery, Anna Maria Sales, Alice Miranda, Nadia Cristina Duppre, Amanda Nogueira Brum Fontes, Tatiana Pereira da Silva, Roberta Olmo Pinheiro and 7 more

Open access · greenAbstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Molecular Surveillance of Antimicrobial Resistance ofInfection and drug resistance · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 3 countries.

Charlotte Avanzi *Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.ORCID 0000-0002-1062-4058
Raquel Cristina Maia *Leprosy Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Andrej BenjakGlobal Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
José Augusto NeryLeprosy Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Anna Maria SalesLeprosy Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Alice MirandaLeprosy Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Nadia Cristina DuppreLeprosy Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Amanda Nogueira Brum FontesMolecular Biology Applied to Diagnosis of Mycobacterial Diseases Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Tatiana Pereira da SilvaLeprosy Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Roberta Olmo PinheiroLeprosy Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Fernanda Neves-MantaLeprosy Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Suelen Justo Maria MoreiraLeprosy Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Philippe BussoGlobal Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Euzenir Nunes SarnoLeprosy Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Phillip Noel SuffysMolecular Biology Applied to Diagnosis of Mycobacterial Diseases Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Stewart Thomas Cole *Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland stewart.cole@pasteur.fr milton.moraes@fiocruz.br.ORCID 0000-0003-1400-5585
Milton Ozório Moraes *Leprosy Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil stewart.cole@pasteur.fr milton.moraes@fiocruz.br.
Fundação Oswaldo Cruz · BRÉcole Polytechnique Fédérale de Lausanne · CHInstitut Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A case of

Indexed as

LeprosyMycobacterium lepraeHumansMutationRecurrenceRifampinRifampinleprosyMycobacterium lepraerelapse emergenceresistancerifampintreatmentwhole-genome sequencing

Identifiers

PMID32340990
PMCPMC7318023
OpenAlexW3018709018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.