Evidence map›Paper›PMID 32340706›Full record

ReviewRheumatic diseases clinics of North America2020

Treat to Target in Axial Spondyloarthritis: Pros, Cons, and Future Directions.

Jean W Liew, Maureen Dubreuil

Abstract readReview
In one paragraph

Review in Rheumatic diseases clinics of North America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Efficacy and Safety of Intravenous Golimumab in Ankylosing Spondylitis Patients With Early and Late Disease Through One Year of the GO-ALIVE Study.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2022
    Trial
  2. The SWITCH algorithm: An expert consensus on treat-to-target criteria for chronic prurigo.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jean W LiewDivision of Rheumatology, Department of Medicine, University of Washington, 1959 Northeast Pacific Street, BB561, Seattle, WA 98195, USA. Electronic address: https://twitter.com/rheum_cat.
Maureen DubreuilSection of Rheumatology, Boston University School of Medicine, 650 Albany Street, X201, Boston, MA 02119, USA. Electronic address: mdubreui@bu.edu.

Funding

RESEARCH TRAINING IN RHEUMATOLOGYT32AR007108 · NIAMS · UNIVERSITY OF WASHINGTON · PI Shaun Jackson, Tomas M Mustelin · 1986 to 2026
$6.6M
Establishing the Value of Treatment Strategies in SpondyloarthritisK23AR069127 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI DUBREUIL, MAUREEN · 2016 to 2020
$848k
NIAMS NIH HHS K23 AR069127NIAMS NIH HHS T32 AR007108
6 · The paper itself

Abstract

Treat to target describes a management paradigm that involves choosing a clinically relevant target, assessment with validated measures at a prespecified frequency, and a change in therapy if the target is not met. Although guidelines recommend treating to target in axial spondyloarthritis (axSpA), ideal methods to reach this target remain controversial. This review focuses on background for a treat-to-target strategy in axSpA. Potential targets of treatment, association of targets with outcomes, evidence of treatment impact on outcomes, and how treat to target has been incorporated into treatment guidelines are discussed. Treat-to-target trials and the research agenda for studies in axSpA are discussed.

Indexed as

Patient Care PlanningHumansPractice Guidelines as TopicSpondylarthritisAnkylosing spondylitisAxial spondyloarthritisDisease activityTreat to target

Identifiers

PMID32340706
PMCPMC8106802

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.