Evidence map›Paper›PMID 32340516›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2020

Significant aortic stenosis associated with poorer functional outcomes in patients with acute ischaemic stroke undergoing endovascular therapy.

Nicholas Jh Ngiam, Benjamin Yq Tan, Ching-Hui Sia, Bernard Pl Chan, Gopinathan Anil, Yang Cunli, Staffan Holmin, Tommy Anderssen, Kian-Keong Poh, Leonard Ll Yeo and 1 more

Open access · greenAbstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Nicholas Jh NgiamDivision of Neurology, Department of Medicine, National University Health System, Singapore, Singapore.ORCID https://orcid.org/0000-0002-3339-7281
Benjamin Yq TanDivision of Neurology, Department of Medicine, National University Health System, Singapore, Singapore.
Ching-Hui SiaYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Bernard Pl ChanDivision of Neurology, Department of Medicine, National University Health System, Singapore, Singapore.
Gopinathan AnilYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Yang CunliDivision of Interventional Radiology, Department of Diagnostic Imaging, National University Health System, Singapore, Singapore.
Staffan HolminDeparment of Neuroradiology, Karolinska University Hospital and Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Tommy AnderssenDeparment of Neuroradiology, Karolinska University Hospital and Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Kian-Keong PohYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Leonard Ll YeoDivision of Neurology, Department of Medicine, National University Health System, Singapore, Singapore.
Vijay K SharmaDivision of Neurology, Department of Medicine, National University Health System, Singapore, Singapore.
National University of Singapore · SGNational University Health System · SGKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimBi-directional feedback mechanisms exist between the heart and brain, which have been implicated in heart failure. We postulate that aortic stenosis may alter cerebral haemodynamics and influence functional outcomes after endovascular thrombectomy for acute ischaemic stroke. We compared clinical characteristics, echocardiographic profile and outcomes in patients with or without aortic stenosis that underwent endovascular thrombectomy for large vessel occlusion acute ischaemic stroke.

methodsConsecutive acute ischaemic stroke patients with anterior and posterior circulation large vessel occlusion (internal carotid artery, middle cerebral artery and basilar artery) who underwent endovascular thrombectomy were studied. Patients were divided into those with significant aortic stenosis (aortic valve area <1.5 cm

resultsWe identified 26 (8.5%) patients with significant aortic stenosis. These patients were older (median age 76 (interquartile range 68-84) vs. 67 (interquartile range 56-75) years,

conclusionIn acute ischaemic stroke patients managed with endovascular thrombectomy, significant aortic stenosis is associated with poor functional outcome despite comparable recanalisation rates. Larger cohort studies are needed to explore this relationship further.

Indexed as

Aortic Valve StenosisBrain IschemiaEndovascular ProceduresIschemic StrokeStrokeAgedHumansRetrospective StudiesThrombectomyTreatment Outcomeacute strokeAortic stenosisendovascular treatmentfunctional recoverythrombectomy

Identifiers

PMID32340516
PMCPMC7724604
OpenAlexW3018770677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.