Evidence map›Paper›PMID 32340364›Full record

ArticleJournal of clinical medicine2020

Validation of Hyponatremia as a Prognostic Predictor in Multiregional Upper Tract Urothelial Carcinoma.

Hsin-Chih Yeh, Ching-Chia Li, Sheng-Chen Wen, Nirmish Singla, Solomon L Woldu, Haley Robyak, Chun-Nung Huang, Hung-Lung Ke, Wei-Ming Li, Hsiang-Ying Lee and 11 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 3 countries.

Hsin-Chih YehDepartment of Urology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung 80145, Taiwan.ORCID 0000-0003-4113-629X
Ching-Chia LiDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Sheng-Chen WenDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.ORCID 0000-0001-5178-2100
Nirmish SinglaDepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0001-9495-6983
Solomon L WolduDepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Haley RobyakDivision of Urology, Department of Surgery, Penn State Health Milton S. Hershey Medical Center, Hershey, PA 17033, USA.ORCID 0000-0002-7409-9547
Chun-Nung HuangDepartment of Urology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung 80145, Taiwan.
Hung-Lung KeDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.ORCID 0000-0002-4208-3858
Wei-Ming LiDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Hsiang-Ying LeeDepartment of Urology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung 80145, Taiwan.ORCID 0000-0003-2405-4874
Chia-Yang LiGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0001-5689-9850
Bi-Wen YehDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 80756, Taiwan.
Sheau-Fang YangGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0002-1773-3716
Hung-Pin TuDepartment of Public Health and Environmental Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Shahrokh F ShariatDepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Arthur I SagalowskyDepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Jay D RamanDivision of Urology, Department of Surgery, Penn State Health Milton S. Hershey Medical Center, Hershey, PA 17033, USA.
Yair LotanDepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0001-5692-2723
Jer-Tsong HsiehDepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-1919-6010
Vitaly MargulisDepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Wen-Jeng WuDepartment of Urology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Kaohsiung Medical University · TWThe University of Texas Southwestern Medical Center · USPenn State Milton S. Hershey Medical Center · USMedical University of Vienna · AT

Funding

Kaohsiung Medical University Hospital KMUH106-6R55Kaohsiung Municipal Ta-Tung Hospital kmtth-104-022Ministry of Science and Technology, Taiwan MOST 105-2628-B-037-004-MY2
6 · The paper itself

Abstract

Hyponatremia has been shown to be associated with prognosis in various cancers, but its role in upper tract urothelial carcinoma (UTUC) is largely unidentified. We created an international multiregional cohort of UTUC, consisting of 524 and 213 patients from Taiwan and the U.S., to validate the significance of hyponatremia. Clinicopathologic characteristics were compared according to the presence of hyponatremia. Univariate and multivariate Cox regression models were used to investigate the association of hyponatremia with disease progression and survival. The impact of hyponatremia in patients from distinct regions was also analyzed. Hyponatremia was found in 143 (19.4%) patients. Hyponatremic patients had significantly worse Eastern Cooperative Oncology Group (ECOG) performance status (

Indexed as

ECOGhyponatremiaprognosisprogressionupper tract urothelial carcinoma

Identifiers

PMID32340364
PMCPMC7231247
OpenAlexW3018064835

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.